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Search results 1110601 to 1110700 out of 1112510 for seed protein

0.738s
Type Details Score
Protein Domain
Name: Cathelicidin-like
Type: Family
Description: Cathelicidins are antimicrobial peptides and, together with defensins, form a large group of cationic peptides with amphipathic properties, and are part of the innate immune system in many vertebrates. These peptides exert antimicrobial activity against a wide range of microorganisms such as bacteria, enveloped viruses and fungi. They were first described in bone marrow myeloid cells from mammals but they are also present in several organisms, as antimicrobial peptides are a conserved immune response in all organisms [, ].Structurally, these proteins consist of a highly conserved N-terminal "cathelin' domain including a signal sequence and a conserved region of about 100 residues that contains four cysteines involved in two disulphide bonds, and a highly divergent C-terminal section of variable size [ ]. It is in this C-terminal section that the antibacterial peptides are found; they are proteolytically processed from their precursor by enzymes such as elastase. This structure is shown in the following schematic representation:+---+--------------------------------+--------------------+ |Sig| Propeptide C C C C | Antibacterial pep. |+---+----------------|--|--|--|------+--------------------+ | | | |+--+ +--+ 'C': conserved cysteine involved in a disulphide bond.Cathelicidins-related peptides from reptiles are also included in this family. They are potent antimicrobial peptides with low cytotoxicity, being interesting candidates as antimicrobial agents [ ].
Protein Domain
Name: Phenylalanine/histidine ammonia-lyases, active site
Type: Active_site
Description: This entry represents the active site of phenylalanine ammonia-lyase (PAL; ) and the mechanistically related protein histidine ammonia lyase (HAL; ). Both contain a catalytic Ala-Ser-Gly triad that is post-translationally cyclised [ ]. PAL is a key biosynthetic catalyst in phenylpropanoid assembly in plants and fungi, and is involved in the biosynthesis of a wide variety of secondary metabolites such as flavanoids, furanocoumarin phytoalexins and cell wall components. These compounds are important for normal growth and in responses to environmental stress. PAL catalyses the removal of an ammonia group from phenylalanine to form trans-cinnamate. HAL catalyses the first step in histidine degradation, the removal of an ammonia group from histidine to produce urocanic acid. The core domain in PAL and Hal share about 30% sequence identity, with PAL containing an additional approximately 160 residues extending from the common fold [].The two types of enzymes are functionally and structurally related [ ]. They are the only enzymes which are known to have the modified amino acid dehydro-alanine (DHA) in their active site. A serine residue has been shown [, , ] to be the precursor of this essential electrophilic moiety. The region around the active site serine is well conserved and has been used as the signature pattern for this entry.
Protein Domain
Name: Elongation factor 1B gamma, C-terminal
Type: Domain
Description: Translation elongation factors are responsible for two main processes during protein synthesis on the ribosome [ , , ]. EF1A (or EF-Tu) is responsible for the selection and binding of the cognate aminoacyl-tRNA to the A-site (acceptor site) of the ribosome. EF2 (or EF-G) is responsible for the translocation of the peptidyl-tRNA from the A-site to the P-site (peptidyl-tRNA site) of the ribosome, thereby freeing the A-site for the next aminoacyl-tRNA to bind. Elongation factors are responsible for achieving accuracy of translation and both EF1A and EF2 are remarkably conserved throughout evolution.Elongation factor EF1B (also known as EF-Ts or EF-1beta/gamma/delta) is a nucleotide exchange factor that is required to regenerate EF1A from its inactive form (EF1A-GDP) to its active form (EF1A-GTP). EF1A is then ready to interact with a new aminoacyl-tRNA to begin the cycle again. EF1B is more complex in eukaryotes than in bacteria, and can consist of three subunits: EF1B-alpha (or EF-1beta), EF1B-gamma (or EF-1gamma) and EF1B-beta (or EF-1delta) [ ].This entry represents a conserved domain usually found near the C terminus of EF1B-gamma chains, a peptide of 410-440 residues. The gamma chain appears to play a role in anchoring the EF1B complex to the beta and delta chains and to other cellular components.
Protein Domain
Name: Translation initiation factor IF6
Type: Family
Description: This family includes eukaryotic translation initiation factor 6 (eIF6) as well as presumed archaeal homologues.The assembly of 80S ribosomes requires joining of the 40S and 60S subunits, which is triggered by the formation of an initiation complex on the 40S subunit. This event is rate-limiting for translation, and depends on external stimuli and the status of the cell. Eukaryotic translation initiation factor 6 (eIF6) binds specifically to the free 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit ribosomes [ ]. Furthermore, eIF6 interacts in the cytoplasm with RACK1, a receptor for activated protein kinase C (PKC). RACK1 is a major component of translating ribosomes, which harbour significant amounts of PKC. Loading 60S subunits with eIF6 caused a dose-dependent translational block and impairment of 80S formation, which are reversed by expression of RACK1 and stimulation of PKC in vivo and in vitro. PKC stimulation leads to eIF6 phosphorylation and its release, promoting 80S subunit formation. RACK1 provides a physical and functional link between PKC signalling and ribosome activation [, , ].All members of this family have a conserved pentameric fold referred to as a beta/alpha propeller. The eukaryotic IF6 members have a moderately conserved C-terminal extension which is not required for ribosomal binding, and may have an alternative function [ ].
Protein Domain
Name: Peptidase C14, caspase domain
Type: Domain
Description: This domain can be found in caspases (MEROPS family C12A) and metacaspases (MEROPS family C14B). Metacaspases adopt a caspase fold, with active site loops arranged similarly as other caspases [ ].Caspases (Cysteine-dependent ASPartyl-specific proteASE) are cysteine peptidases [ ]. They are tightly regulated proteins that require zymogen activation to become active, and once active can be regulated by caspase inhibitors. Caspases are mainly involved in mediating cell death (apoptosis) [, , ]. They have two main roles within the apoptosis cascade: as initiators that trigger the cell death process, and as effectors of the process itself. Caspases can have roles other than in apoptosis, such as caspase-1 (interleukin-1 beta convertase) (), which is involved in the inflammatory process. The activation of apoptosis can sometimes lead to caspase-1 activation, providing a link between apoptosis and inflammation, such as during the targeting of infected cells. Caspases may also be involved in cell differentiation [ ].Metacaspases are arginine/lysine-specific, in contrast to caspases, which are aspartate-specific. They are found only in plants [ , ], fungi [] and lower eukaryotes, including the protozoa []. While plant metacaspases have been shown to be involved in cell death pathways, in other organisms they have evolved alternative functions [].
Protein Domain
Name: 3'5'-cyclic nucleotide phosphodiesterase N-terminal
Type: Domain
Description: The cyclic nucleotide phosphodiesterases (PDE) comprise a group of enzymes that degrade the phosphodiester bond in the second messenger molecules cAMP and cGMP. They are divided into 11 families. They regulate the localisation, duration and amplitude of cyclic nucleotide signalling within subcellular domains. PDEs are therefore important for signal transduction.PDE enzymes are often targets for pharmacological inhibition due to their unique tissue distribution, structural properties, and functional properties. Inhibitors include: Roflumilast for chronic obstructive pulmonary disease and asthma [ ], Sildenafil for erectile dysfunction [] and Cilostazol for peripheral arterial occlusive disease [], amongst others.Retinal 3',5'-cGMP phosphodiesterase is located in photoreceptor outer segments: it is light activated, playing a pivotal role in signal transduction. In rod cells, PDE is oligomeric, comprising an alpha-, a beta- and 2 gamma-subunits, while in cones, PDE is a homodimer of alpha chains, which are associated with several smaller subunits. Both rod and cone PDEs catalyse the hydrolysis of cAMP or cGMP to the corresponding nucleoside 5' monophosphates, both enzymes also binding cGMP with high affinity. The cGMP-binding sites are located in the N-terminal half of the protein sequence, while the catalytic core resides in the C-terminal portion.This domain is found to the N terminus of the calcium/calmodulin-dependent 3'5'-cyclic nucleotide phosphodiesterase domain ( ).
Protein Domain
Name: DUS-like, FMN-binding domain
Type: Domain
Description: This entry represents a dihydrouridine synthase-like (DUS-like) FMN-binding domain [ ]. Proteins containing this domain catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also in some archaea. Most dihydrouridines are found in the D loop of t-RNAs. The role of dihydrouridine in tRNA is currently unknown, but may increase conformational flexibility of the tRNA. It is likely that different family members have different substrate specificities, which may overlap [, ]. 1VHN, a putative flavin oxidoreductase, has high sequence similarity to DUS. The enzymatic mechanism of 1VHN is not known at the present [].Dihydrouridine synthases (Dus) is a large family of flavoenzymes comprising eight subfamilies. They catalyse the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Mainly, they contain two functional conserved domains, an N-terminal catalytic domain (TBD) adopting a TIM barrel fold and a unique C-terminal helical domain (HD) devoted to tRNA recognition. However, DUS2 is distinguished from its paralogues and its fungi orthologues by the acquisition of an additional domain, a double stranded RNA binding domain (dsRBD), which serves as the main tRNA binding module [ , ].
Protein Domain
Name: Angiotensinogen, serpin domain
Type: Domain
Description: Angiotensinogen is a component of the renin-angiotensin system (RAS), a hormone system that regulates blood pressure and fluid balance. It is also known as the renin substrate, and is a non-inhibitory member of the serpin family of proteinase inhibitors (MEROPS inhibitor family I4, clan ID, MEROPS identifier I04.953).Angiotensinogen is catalytically cleaved by renin to produce angiotensin I in response to lowered blood pressure. Angiotensin converting enzyme (ACE), subsequently removes a dipeptide to produce angiotensin II, the physiologically active peptide, which functions in the regulation of volume and mineral balance of body fluids [ , ]. Angiotensin I and angiotensin II can be further processed to generate angiotensin III, which stimulates aldosterone release [], and angiotensin IV. Angiotensin 1-9 is cleaved from angiotensin-1 by ACE2 [] and can be further processed by ACE to produce angiotensin 1-7, angiotensin 1-5 and angiotensin 1-4 [, ].Angiotensinogen is synthesised in the liver and secreted in plasma [ , , , ]. Angiotensinogen appears to be associated with a predisposition to essential hypertension; it is also associated with pregnancy-induced hypertension (pih) (preeclampsia), a heterogeneous disorder that complicates 5-7% of all pregnancies and remains a leading cause of maternal, foetal and neonatal morbidity and mortality [].This entry represents the serpin domain of angiotensinogen.
Protein Domain
Name: CBM6/CBM35/CBM36-like 2
Type: Domain
Description: Carbohydrate binding module family 6 (CBM6, family 6 CBM), also known as cellulose binding domain family VI (CBD VI), and related CBMs (CBM35 and CBM36). These are non-catalytic carbohydrate binding domains found in a range of enzymes that display activities against a diverse range of carbohydrate targets, including mannan, xylan, beta-glucans, cellulose, agarose, and arabinans [ ]. These domains facilitate the strong binding of the appended catalytic modules to their dedicated, insoluble substrates. Many of these CBMs are associated with glycoside hydrolase (GH) domains. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the β-sandwich fold [, , ]. CBM36s are calcium-dependent xylan binding domains []. CBM35s display conserved specificity through extensive sequence similarity, but divergent function through their appended catalytic modules [, , ].This domain is related to carbohydrate binding modules CBM6/CBM35/CBM36 and is found in xanthan lyase, which cleaves the linkage between the terminal mannosyl and glucuronyl residues of the side chain of xanthan to liberate pyruvylated mannose [ ], and in golvesin, which is a membrane-bound protein from endosomes, vacuole and golgi found in Dictyostelium [].
Protein Domain
Name: Tumour necrosis factor receptor 13C
Type: Family
Description: The tumour necrosis factor (TNF) receptor (TNFR) superfamily comprises more than 20 type-I transmembrane proteins. Family members are defined based on similarity in their extracellular domain -a region that contains many cysteine residues arranged in a specific repetitive pattern [ ]. The cysteines allow formation of an extended rod-like structure, responsible for ligand binding []. Upon receptor activation, different intracellular signalling complexes are assembled for different members of the TNFR superfamily, depending on their intracellular domains and sequences [ ]. Activation of TNFRs can therefore induce a range of disparate effects, including cell proliferation, differentiation, survival, or apoptotic cell death, depending upon the receptor involved [, ]. TNFRs are widely distributed and play important roles in many crucial biological processes, such as lymphoid and neuronal development, innate and adaptive immunity, and maintenance of cellular homeostasis [ ]. Drugs that manipulate their signalling have potential roles in the prevention and treatment of many diseases, such as viral infections, coronary heart disease, transplant rejection, and immune disease []. TNF receptor 13C is also known as B-cell activating factor (BAFF) receptor [ ]. It appears to be the principal receptor in mediating BAFF-dependent B-cell signalling, and plays a critical role in late-stage B-cell maturation and survival [].
Protein Domain
Name: Tumor necrosis factor receptor 1B, N-terminal
Type: Domain
Description: Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B, also known as TNFR2, type 2 TNFR, TNFBR, TNFR80, TNF-R75, TNF-R-II, p75, CD120b) binds TNF-alpha, but lacks the death domain (DD) that is associated with the cytoplasmic domain of TNFRSF1A (TNFR1) [ ]. It is inducible and expressed exclusively by oligodendrocytes, astrocytes, T cells, thymocytes, myocytes, endothelial cells, and in human mesenchymal stem cells []. TNFRSF1B protects oligodendrocyte progenitor cells (OLGs) against oxidative stress, and induces the up-regulation of cell survival genes []. While pro-inflammatory and pathogen-clearing activities of TNF are mediated mainly through activation of TNFRSF1A, a strong activator of NF-kappaB, TNFRSF1B is more responsible for suppression of inflammation []. Although the affinities of both receptors for soluble TNF are similar, TNFRSF1B is sometimes more abundantly expressed and thought to associate with TNF, thereby increasing its concentration near TNFRSF1A receptors, and making TNF available to activate TNFRSF1A (a ligand-passing mechanism) [].This entry represents the N-terminal domain of TNFR1B. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
Protein Domain
Name: C4-dicarboxylate anaerobic carrier-like
Type: Family
Description: Escherichia coli contains four different secondary carriers (DcuA, DcuB, DcuC, and DctA) for C4-dicarboxylates [ , , , ] DcuA is used for aerobic growth on C4-dicarboxylates [, ], whereas the Dcu carriers (encoded by the dcuA, dcuB, and dcuC genes) are used under anaerobic conditions and form a distinct family of carriers [, , , , , ]. Each of the Dcu carriers is able to catalyze the uptake, antiport, and possibly also efflux of C4-dicarboxylates. DcuB is the major C4-dicarboxylate carrier for fumarate respiration with high fumarate-succinate exchange activity. It is synthesized only in the absence of oxygen and nitrate and in the presence of C4-dicarboxylates [, , , ]. DcuA is expressed constitutively in aerobic and anaerobic growth and can substitute for DcuB [, ]. These proteins are members of the C4-dicarboxylate Uptake C (DcuC) family. DcuC has 12 GES predicted transmembrane regions, is induced only under anaerobic conditions, and is not repressed by glucose. DcuC may therefore function as a succinate efflux system during anaerobic glucose fermentation. However, when overexpressed, it can replace either DcuA or DcuB in catalyzing fumarate-succinate exchange and fumarate uptake [ , ]. DcuC shows the same transport modes as DcuA and DcuB (exchange, uptake, and presumably efflux of C4-dicarboxylates) [].
Protein Domain
Name: C4-dicarboxylate anaerobic carrier
Type: Family
Description: Escherichia coli contains four different secondary carriers (DcuA, DcuB, DcuC, and DctA) for C4-dicarboxylates [ , , , ] DcuA is used for aerobic growth on C4-dicarboxylates [, ], whereas the Dcu carriers (encoded by the dcuA, dcuB, and dcuC genes) are used under anaerobic conditions and form a distinct family of carriers [, , , , , ]. Each of the Dcu carriers is able to catalyze the uptake, antiport, and possibly also efflux of C4-dicarboxylates. DcuB is the major C4-dicarboxylate carrier for fumarate respiration with high fumarate-succinate exchange activity. It is synthesized only in the absence of oxygen and nitrate and in the presence of C4-dicarboxylates [, , , ]. DcuA is expressed constitutively in aerobic and anaerobic growth and can substitute for DcuB [, ]. These proteins are members of the C4-dicarboxylate Uptake C (DcuC) family. DcuC has 12 GES predicted transmembrane regions, is induced only under anaerobic conditions, and is not repressed by glucose. DcuC may therefore function as a succinate efflux system during anaerobic glucose fermentation. However, when overexpressed, it can replace either DcuA or DcuB in catalyzing fumarate-succinate exchange and fumarate uptake [ , ]. DcuC shows the same transport modes as DcuA and DcuB (exchange, uptake, and presumably efflux of C4-dicarboxylates) [].
Protein Domain
Name: Flap endonuclease
Type: Family
Description: This entry represents a family of proteins that includes flap endonucleases from bacteria and viruses. Flap endonucleases (FENs) catalyse the exonucleolytic hydrolysis of blunt-ended duplex DNA substrates and the endonucleolytic cleavage of 5'-bifurcated nucleic acids at the junction formed between single and double-stranded DNA [ ].Escherichia phage T5 encodes the flap endonuclease D15, which catalyzes both the 5'-exonucleolytic and structure-specific endonucleolytic hydrolysis of DNA branched nucleic acid molecules [ , , ]. In bacteriophage T4, disruption of the rnh gene (which encodes a FEN, known historically as T4 RNase H) results in slower, less accurate DNA replication. Bacteriophage T4 has both 5' nuclease and flap endonuclease activities []. In prokaryotes, the essential FEN reaction can be performed by the N-terminal 5'-3' exonuclease domain present on DNA polymerase I. Some eubacteria, however, possess a second FEN-encoding gene, in addition to their DNA polymerase I FEN domain [ , ]. Two distinct classes of these independent bacterial FENs exist: ExoIX (Xni) from Escherichia coli and SaFEN (Staphylococcus aureus FEN). SaFEN has both FEN and 5'-3' exonuclease activities. Xni (also known as YgdG) was previously identified as a 3'-5' exonuclease and named exonuclease IX (exonuclease 9) [, ] but subsequently found to possess flap endonuclease activity, but not exonuclease activity [, , ].
Protein Domain
Name: Transforming growth factor beta-1 proprotein
Type: Family
Description: The transforming growth factors-beta constitute a family of multi-functional cytokines that regulate cell growth and differentiation []. Many cells synthesise TGF-beta, and essentially all have specific receptors for this peptide []. TGF-beta regulates the actions of many other peptide growth factors and determines a positive or negative direction of their effects. The protein functions as a disulphide-linked homodimer. Its sequence is characterised by the presence of several C-terminal cysteine residues, which form interlocking disulphide links arranged in a knot-like topology. A similar "cystine-knot"arrangement has been noted in the structures of some enzyme inhibitors and neurotoxins that bind to voltage-gated Ca2+ channels, although the precise topology differs.The three-dimensional structures of several members of the TGF-beta super-family have been deduced [, , ]. TGF-beta genes are expressed differentially, suggesting that the various TGF-beta species may have distinct physiological roles in vivo. The solution structure of human TGF-beta 1 was determined using multinuclear magnetic resonance spectroscopy with hybrid distance geometry/simulated annealing [ ]. The structure shows a high degree of similarity to that of TGF-beta 2, but with notable differences in structure and flexibility. Examination of TGF-beta 1 mRNA levels in adult murine tissues indicates that expression is predominant in spleen, lung and placenta []. TGF-beta 1 is believed to play important roles in pathologic processes.
Protein Domain
Name: Conotoxin
Type: Family
Description: Cone snail toxins, conotoxins, are small neurotoxic peptides with disulphide connectivity that target ion-channels or G-protein coupled receptors. Based on the number and pattern of disulphide bonds and biological activities, conotoxins can be classified into several families [ ]. Omega, delta and kappa families of conotoxins have a knottin or inhibitor cysteine knot scaffold. The knottin scaffold is a very special disulphide-through-disulphide knot, in which the III-VI disulphide bond crosses the macrocycle formed by two other disulphide bonds (I-IV and II-V) and the interconnecting backbone segments, where I-VI indicates the six cysteine residues starting from the N terminus. The disulphide bonding network, as well as specific amino acids in inter-cysteine loops, provide the specificity of conotoxins [ ]. The cysteine arrangements are the same for omega, delta and kappa families, even though omega conotoxins are calcium channel blockers, whereas delta conotoxins delay the inactivation of sodium channels, and kappa conotoxins are potassium channel blockers []. Mu conotoxins have two types of cysteine arrangements, but the knottin scaffold is not observed. Mu conotoxins target the voltage-gated sodium channels [, ], and are useful probes for investigating voltage-dependent sodium channels of excitable tissues []. Alpha conotoxins have two types of cysteine arrangements [], and are competitive nicotinic acetylcholine receptor antagonists.
Protein Domain
Name: Somatostatin
Type: Family
Description: Somatostatin (SST) also known as somatotropin release-inhibiting factor (SRIF), is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Somatostatin, acting through the 5 somatostatin receptors, it has been found to regulate the secretion of various hormones such as pituitary growth hormone (GH) [ ], thyroid-stimulating hormone (TSH) [], prolactin [], pituitary, insulin [] and glucagon []. It also inhibits secretion in the intestine (including gastric acid in the stomach) [], pancreatic acinar cells and pancreatic beta-cells [, ], cell proliferation [], stimulates absorption in the intestine and modulates smooth muscle contractility []. Somatostatin has a wide distribution throughout the central nervous system as well as in peripheral tissues, for example in the pituitary, pancreas and stomach and is released from the hypothalamus. In the CNS, it is a neurotransmitter and neuromodulator activating a hyperpolarising K+ current and inhibiting Ca2+ influx, and is believed to play important roles in regulating locomotor activity and cognitive function. These various actions are mediated by a family of seven transmembrane domain G protein-coupled receptors that comprise of five distinct subtypes: Somatostatin receptor 1 (SSTR1), Somatostatin receptor 2 (SSTR2), Somatostatin receptor 3 (SSTR3), Somatostatin receptor 4 (SSTR4) and Somatostatin receptor 5 (SSTR5) [, , ].This entry represents the somatostatin family, including somatostatin and cortistatin from humans.
Protein Domain
Name: Tumour necrosis factor receptor 4
Type: Family
Description: The tumour necrosis factor (TNF) receptor (TNFR) superfamily comprises more than 20 type I transmembrane proteins. Family members are defined based on similarity in their extracellular domain, a region that contains many cysteine residues arranged in a specific repetitive pattern [ ]. The cysteines allow formation of an extended rodlike structure, responsible for ligand binding []. Upon receptor activation, different intracellular signalling complexes are assembled for different members of the TNFR superfamily, depending on their intracellular domains and sequences [ ]. Activation of TNFRs can therefore induce a range of disparate effects, including cell proliferation, differentiation, survival, or apoptotic cell death, depending upon the receptor involved [, ]. TNFRs are widely distributed and play important roles in many crucial biological processes, such as lymphoid and neuronal development, innate and adaptive immunity, and maintenance of cellular homeostasis [ ]. Drugs that manipulate their signalling have potential roles in the prevention and treatment of many diseases, such as viral infections, coronary heart disease, transplant rejection, and immune disease []. This entry represents TNF receptor 4 (also known as OX40 and CD134 antigen) is expressed primarily on activated CD4(+) T cells. Activation of the receptor increases the proinflammatory activity of these cells and enhances their long-term survival [ ].
Protein Domain
Name: Venom nerve growth factor
Type: Family
Description: During the development of the vertebrate nervous system, many neurons become redundant (because they have died, failed to connect to target cells, etc.) and are eliminated. At the same time, developing neurons send out axon outgrowths that contact their target cells [ ]. Such cells control their degree of innervation (the number of axon connections) by the secretion of various specific neurotrophic factors that are essential for neuron survival. One of these is nerve growth factor (NGF), which is involved in the survival of some classes of embryonic neuron (e.g., peripheral sympathetic neurons) []. NGF is mostly found outside the central nervous system (CNS), but slight traces have been detected in adult CNS tissues, although a physiological role for this is unknown []; it has also been found in several snake venoms [, ]. Proteins similar to NGF include brain-derived neurotrophic factor (BDNF) and neurotrophins 3 to 7, all of which demonstrate neuron survival and outgrowth activities. In contrast to mammalian NGFs, which exist as multimeric complexes of alpha, beta and gamma subunits, snake venom NGFs exist almost exclusively as beta-chains [ ]. They act as low-potency neurotrophic tyrosine kinase receptor type 1 (NTRK1; also called TrkA) agonists [], and have been shown to promote survival and differentiation of cultured cells [].
Protein Domain
Name: Tumour necrosis factor receptor 5
Type: Family
Description: The tumour necrosis factor (TNF) receptor (TNFR) superfamily comprises more than 20 type-I transmembrane proteins. Family members are defined based on similarity in their extracellular domain - a region that contains many cysteine residues arranged in a specific repetitive pattern [ ]. The cysteines allow formation of an extended rod-like structure, responsible for ligand binding []. Upon receptor activation, different intracellular signalling complexes are assembled for different members of the TNFR superfamily, depending on their intracellular domains and sequences [ ]. Activation of TNFRs can therefore induce a range of disparate effects, including cell proliferation, differentiation, survival, or apoptotic cell death, depending upon the receptor involved [, ]. TNFRs are widely distributed and play important roles in many crucial biological processes, such as lymphoid and neuronal development, innate and adaptive immunity, and maintenance of cellular homeostasis [ ]. Drugs that manipulate their signalling have potential roles in the prevention and treatment of many diseases, such as viral infections, coronary heart disease, transplant rejection, and immune disease []. TNF receptor 5 (also known as CD40 antigen) is expressed by a wide variety of cell types, including B lymphocytes, macrophages, dendritic cells, endothelial cells and epithelial cells. The receptor plays an important role in T cell-mediated B lymphocyte activation [ ].
Protein Domain
Name: Aldo-keto reductase family 2A
Type: Family
Description: This entry represents aldo-keto reductase family 2A (AKR2A), which includes NADP-S6PDH from Malus domestica (Apple) [ ], and AKR2A2 (or NADPH-M6PR) from Apium graveolens (Celery) [].In general, the aldo-keto reductase (AKR) protein superfamily members reduce carbonyl substrates such as: sugar aldehydes, keto-steroids, keto-prostaglandins, retinals, quinones, and lipid peroxidation by-products [ , ]. However, there are some exceptions, such as the reduction of steroid double bonds catalysed by AKR1D enzymes (5beta-reductases); and the oxidation of proximate carcinogen trans-dihydrodiol polycyclic aromatic hydrocarbons; while the beta-subunits of potassium gated ion channels (AKR6 family) control Kv channel opening [ ].Structurally, they contain an (alpha/beta)8-barrel motif, display large loops at the back of the barrel which govern substrate specificity, and have a conserved cofactor binding domain. The binding site is located in a large, deep, elliptical pocket in the C-terminal end of the beta sheet, the substrate being bound in an extended conformation. The hydrophobic nature of the pocket favours aromatic and apolar substrates over highly polar ones [ ]. They catalyse an ordered bi bi kinetic mechanism in which NAD(P)H cofactor binds first and leaves last []. Binding of the NADPH coenzyme causes a massive conformational change, reorienting a loop, effectively locking the coenzyme in place. This binding is more similar to FAD- than to NAD(P)-binding oxidoreductases [].
Protein Domain
Name: Aldo-keto reductase family 2B
Type: Family
Description: This entry represents aldo-keto reductase family 2B (AKR2B), which includes XR from Candida tropicalis. XR catalyses the NAD(P)H dependent reduction of xylose to xylitol [ ].In general, the aldo-keto reductase (AKR) protein superfamily members reduce carbonyl substrates such as: sugar aldehydes, keto-steroids, keto-prostaglandins, retinals, quinones, and lipid peroxidation by-products [ , ]. However, there are some exceptions, such as the reduction of steroid double bonds catalysed by AKR1D enzymes (5beta-reductases); and the oxidation of proximate carcinogen trans-dihydrodiol polycyclic aromatic hydrocarbons; while the beta-subunits of potassium gated ion channels (AKR6 family) control Kv channel opening [].Structurally, they contain an (alpha/beta)8-barrel motif, display large loops at the back of the barrel which govern substrate specificity, and have a conserved cofactor binding domain. The binding site is located in a large, deep, elliptical pocket in the C-terminal end of the beta sheet, the substrate being bound in an extended conformation. The hydrophobic nature of the pocket favours aromatic and apolar substrates over highly polar ones [ ]. They catalyse an ordered bi bi kinetic mechanism in which NAD(P)H cofactor binds first and leaves last []. Binding of the NADPH coenzyme causes a massive conformational change, reorienting a loop, effectively locking the coenzyme in place. This binding is more similar to FAD- than to NAD(P)-binding oxidoreductases [].
Protein Domain
Name: IAA-amino acid hydrolase ILR1-like
Type: Family
Description: In higher plants, the growth regulator indole-3-acetic acid (IAA or auxin) is found both free and conjugated via amide bonding to a variety of amino acids and peptides, and via an ester linkage to carbohydrates. IAA-Asp conjugates are involved in homeostatic control, protection, storing and subsequent use of free IAA. IAA-Asp is also found in some plants as a unique intermediate for entering into IAA non-decarboxylative oxidative pathway. IAA amidohydrolases, which belong to the M20 family of peptidases, cleave the amide bond between the auxin and the conjugated amino acid to regulate IAA levels [ ].IAA-amino acid hydrolase ILR1 (IAA-LEUCINE RESISTANT 1) from Arabidopsis hydrolyses certain amino acid conjugates of IAA, including IAA-Phe, IAA-Leu and IAA-Tyr, although it can also use IAA-Ala, IAA-Gly, IAA-Met and IAA-Glu as substrates with lower efficiency, having no activity with IAA-Ile, IAA-1-O-beta-D-glucose or IAA-myo-inositol [ , , ]. ILL4, also known as IAR3, hydrolyses IAA-Ala, IAA-Asn, IAA-Cys, IAA-Glu, IAA-Met, IAA-Ser and IAA-Gly [, ] and has a lower efficiency with IAA-Phe, IAA-Leu and IAA-Val and no activity with IAA-Ile [, ]. ILL4 also hydrolyses amino acid conjugates of jasmonic acid and 12-hydroxy jasmonic acid [].This entry includes ILR1 and ILR1-like proteins (ILL) from Arabidopsis thaliana and Oryza sativa.
Protein Domain
Name: Signal transduction histidine kinase, NreB
Type: Family
Description: Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions [ ]. Some bacteria can contain up to as many as 200 two-component systems that need tight regulation to prevent unwanted cross-talk []. These pathways have been adapted to response to a wide variety of stimuli, including nutrients, cellular redox state, changes in osmolarity, quorum signals, antibiotics, and more []. Two-component systems are comprised of a sensor histidine kinase (HK) and its cognate response regulator (RR) []. The HK catalyses its own auto-phosphorylation followed by the transfer of the phosphoryl group to the receiver domain on RR; phosphorylation of the RR usually activates an attached output domain, which can then effect changes in cellular physiology, often by regulating gene expression. Some HK are bifunctional, catalysing both the phosphorylation and dephosphorylation of their cognate RR. The input stimuli can regulate either the kinase or phosphatase activity of the bifunctional HK.This entry represents signal transduction histidine kinases such as NreB. The nreABC (nitrogen regulation) operon encodes a two-component regulatory system that controls dissimilatory nitrate/nitrite reduction in response to oxygen in staphylococci. NreB is a cytosolic protein with four N-terminal cysteine residues, where both the cysteine cluster and iron ions are required for function [ ].
Protein Domain
Name: Bordetella uptake gene
Type: Family
Description: Bordetella pertussis, the causative agent of human whooping cough (pertussis), is an obligate human pathogen with diverse high-affinity transport systems for the assimilation of iron, a biometal that is essential for growth [ ]. Periplasmic binding proteins of a new family, particularly well represented in this organism (and more generally in beta-proteobacteria), have been called Bug receptors [].They adopt a characteristic Venus flytrap fold with two globular domains bisected by a ligand-binding cleft. The family is specific for carboxylated solutes, with a characteristic mode of binding involving two highly conserved beta strand-beta turn-alpha helix motifs originating from each domain. These two motifs form hydrogen bonds with a carboxylate group of the ligand, both directly and via conserved water molecules, and have thus been termed the carboxylate pincers. Domain 1 recognises the ligand and the carboxylate group serves as an initial anchoring point. Domain 2 discriminates between productively and non-productively bound ligands as proper interactions with this domain is needed for the of the closed conformation [ ].BugE has a glutamate bound ligand. No charged residues are involved in glutamate binding by BugE, unlike what has been described for all glutamate receptors reported so far. The Bug architecture is highly conserved despite limited sequence identity [].
Protein Domain
Name: Alpha/beta hydrolase fold-5
Type: Domain
Description: The α/β hydrolase fold [ ] is common to a number of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function. The core of each enzyme is an α/β-sheet (rather than a barrel), containing 8 strands connected by helices []. The enzymes are believed to have diverged from a common ancestor, preserving the arrangement of the catalytic residues. All have a catalytic triad, the elements of which are borne on loops, which are the best conserved structural features of the fold. Esterase (EST) from Pseudomonas putida is a member of the α/β hydrolase fold superfamily of enzymes [].In most of the family members the β-strands are parallel, but some have an inversion of the first strands, which gives it an antiparallel orientation. The catalytic triad residues are presented on loops. One of these is the nucleophile elbow and is the most conserved feature of the fold. Some other members lack one or all of the catalytic residues. Some members are therefore inactive but others are involved in surface recognition. The ESTHER database [ ] gathers and annotates all the published information related to gene and protein sequences of this superfamily [].This entry matches a diverse range of alpha/beta hydrolase enzymes, including a cutinase from unknown prokaryotic organism from soil [ , ].
Protein Domain
Name: Condensin complex subunit 1, C-terminal
Type: Domain
Description: Condensin is a multi-subunit protein complex that acts as an essential regulator of chromosome condensation [ , ]. It contains both SMC (structural maintenance of chromosomes) and non-SMC subunits. Condensin plays an important role during mitosis in the compaction and resolution of chromosomes to remove and prevent catenations that would otherwise inhibit segregation. This is thought to be achieved by the introduction of positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. During interphase condensin promotes clustering of dispersed loci into subnuclear domains and inhibits associations between homologues. In meiosis, condensin has been shown to influence the number of crossover events by regulating programmed double-strand breaks. Roles in gene regulation and lymphocyte development have also been defined.Condensin subunit 1 (known as Cnd1 in Schizosaccharomyces pombe (Fission yeast), and XCAP-D2 in Xenopus laevis laevis) represents one of the non-SMC subunits in the complex. This subunit is phosphorylated at several sites by Cdc2. This phosphorylation process increases the supercoiling activity of condensin [ , ].This entry represents the conserved C-terminal domain of Cnd1. It is also found in non-SMC subunit D3 of condensin II, a second condensin complex present in vertebrates [ ].
Protein Domain
Name: Butanol dehydrogenase-like
Type: Family
Description: Butanol dehydrogenase (BDH) is involved in the final step of the butanol formation pathway, in which it catalyses the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidised in the process. The NADH-BDH has higher activity with longer chained aldehydes and is inhibited by metabolites containing an adenine moiety. This protein family belongs to the so-called iron-containing alcohol dehydrogenase superfamily. Members in this family use divalent ions, preferentially iron or zinc []. This family also includes E. coli YqhD enzyme, an NADP-dependent dehydrogenase whose activity measurements with several alcohols demonstrate preference for alcohols longer than C3 [, ]. The active site of YqhD contains a zinc atom, and a modified NADPH cofactor bearing OH groups on the saturated C5 and C6 atoms, possibly due to oxygen stress on the enzyme, which would functionally work under anaerobic conditions.This entry also includes Long-chain-alcohol dehydrogenase 2 from Geobacillus thermodenitrificans which is able to oxidise a broad range of alkyl alcohols from methanol to 1-triacontanol (C1 to C30), whose best substrate is 1-octanol. In contrast to other members of the family, it apparently does not use iron or other metals as cofactor [ ]. Aldehyde-alcohol dehydrogenase has both aldehyde and alcohol dehydrogenase activities. It can use acetaldehyde, butyraldehyde, butanol and ethanol.
Protein Domain
Name: Nuclear receptor coactivator
Type: Family
Description: This group represents the nuclear receptor coactivator family, also known as the SRC/p160 nuclear receptor coactivator family, which contains proteins that are ligand-dependent transcription factors [ ]. These receptors can function as molecular switches [].NCOA1 directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion [ ]. It is involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs) []. It is also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors [, , ]. It plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors []. It can be regulated by sumoylation and ubiquitination []. NCOA2 is a transcriptional coactivator for steroid receptors and nuclear receptors. It functions as a coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) [ ]. Together with NCOA1, it is required to control energy balance between white and brown adipose tissues []. NCOA3 is overexpressed in a fraction of breast cancers and has been linked to prognosis and tamoxifen resistance [ , ].
Protein Domain
Name: Dynein heavy chain, domain 2, N-terminal
Type: Homologous_superfamily
Description: Dyneins are described as motor proteins of eukaryotic cells, as they can convert energy derived from the hydrolysis of ATP to force and movement along cytoskeletal polymers, such as microtubules. Dyneins generally contain one to three heavy chains, which belong to the AAA+ superfamily of mechanochemical enzymes [ ]. Each heavy chain consists of a flexible N-terminal tail known as the cargo-binding domain [] and a motor domain which consists of an ATP-hydrolysing AAA+ ring, a flexible microtubule-binding stalk, a linker and a C-sequence []. The stalk has an ATP-sensitive microtubule-binding site (MTBD) at its tip [, ], whereas the linker has been suggested to function as a mechanical element for generating dynein's power stroke [, , ].The two categories of dyneins are the axonemal dyneins, which produce the bending motions that propagate along cilia and flagella, and the cytosolic dyneins, which drive a variety of fundamental cellular processes including nuclear migration, organisation of the mitotic spindle, chromosome separation during mitosis, and the positioning and function of many intracellular organelles. Cytoplasmic dyneins contain several accessory subunits ranging from light to intermediate chains.This superfamily represents the N-terminal part of the second domain of dynein heavy chain. No function seems to have been attributed specifically to this region.
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2268  
Description: homeobox-leucine zipper protein ATHB-6-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 5284  
Description: Protein kinase superfamily protein; IPR011009 (Protein kinase-like domain), IPR015943 (WD40/YVTN repeat-like-containing domain), IPR016024 (Armadillo-type fold); GO:0004672 (protein kinase activity), GO:0004674 (protein serine/threonine kinase activity), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1607  
Description: dual specificity protein phosphatase 1-like [Glycine max]; IPR000340 (Dual specificity phosphatase, catalytic domain), IPR024950 (Dual specificity phosphatase); GO:0004725 (protein tyrosine phosphatase activity), GO:0006470 (protein dephosphorylation), GO:0008138 (protein tyrosine/serine/threonine phosphatase activity), GO:0016311 (dephosphorylation), GO:0016791 (phosphatase activity)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1621  
Description: homeobox-leucine zipper protein HAT5-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 3124  
Description: Protein kinase family protein; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2322  
Description: WD repeat-containing protein 61-like isoform 1 [Glycine max]; IPR014906 (Pre-mRNA processing factor 4 (PRP4)-like), IPR015943 (WD40/YVTN repeat-like-containing domain), IPR020472 (G-protein beta WD-40 repeat), IPR027106 (U4/U6 small nuclear ribonucleoprotein Prp4); GO:0005515 (protein binding), GO:0008380 (RNA splicing)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 3378  
Description: receptor-like protein kinase 2; IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 3150  
Description: protein phosphatase 2C 16-like isoform X4 [Glycine max]; IPR001932 (Protein phosphatase 2C (PP2C)-like domain), IPR011009 (Protein kinase-like domain), IPR015655 (Protein phosphatase 2C); GO:0003824 (catalytic activity), GO:0004672 (protein kinase activity), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1854  
Description: trihelix transcription factor GT-1-like isoform 1 [Glycine max]; IPR009057 (Homeodomain-like), IPR027775 (C2H2- zinc finger protein family); GO:0003677 (DNA binding), GO:0003682 (chromatin binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1371  
Description: zinc finger CCCH domain-containing protein 69-like isoform X1 [Glycine max]; IPR000571 (Zinc finger, CCCH-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR026290 (Putative E3 ubiquitin-protein ligase, makorin-related); GO:0005515 (protein binding), GO:0008270 (zinc ion binding), GO:0046872 (metal ion binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1842  
Description: receptor-like protein kinase 2; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1902  
Description: homeobox-leucine zipper protein ATHB-6-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 5029  
Description: chromodomain-helicase-DNA-binding protein 1-like isoform X2 [Glycine max]; IPR000330 (SNF2-related), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR016197 (Chromo domain-like), IPR027417 (P-loop containing nucleoside triphosphate hydrolase); GO:0003677 (DNA binding), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0008270 (zinc ion binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1686  
Description: zinc finger CCCH domain-containing protein 69-like isoform X1 [Glycine max]; IPR000571 (Zinc finger, CCCH-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR026290 (Putative E3 ubiquitin-protein ligase, makorin-related); GO:0005515 (protein binding), GO:0008270 (zinc ion binding), GO:0046872 (metal ion binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1702  
Description: homeobox-leucine zipper protein ATHB-20-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2280  
Description: signal recognition particle subunit SRP68-like [Glycine max]; IPR026258 (Signal recognition particle subunit SRP68); GO:0005047 (signal recognition particle binding), GO:0006614 (SRP-dependent cotranslational protein targeting to membrane), GO:0008312 (7S RNA binding), GO:0030942 (endoplasmic reticulum signal peptide binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1401  
Description: ADP-ribosylation factor GTPase-activating protein AGD12 isoform X1 [Glycine max]; IPR000008 (C2 domain), IPR001164 (Arf GTPase activating protein); GO:0005515 (protein binding), GO:0008060 (ARF GTPase activator activity), GO:0008270 (zinc ion binding), GO:0032312 (regulation of ARF GTPase activity)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1313  
Description: homeobox-leucine zipper protein ATHB-6-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2664  
Description: Protein kinase superfamily protein; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR025875 (Leucine rich repeat 4); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 3406  
Description: receptor-like protein kinase 2; IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 3517  
Description: dynamin-like protein 6; IPR000375 (Dynamin central domain), IPR001401 (Dynamin, GTPase domain), IPR011993 (Pleckstrin homology-like domain), IPR020850 (GTPase effector domain, GED), IPR022812 (Dynamin superfamily), IPR027417 (P-loop containing nucleoside triphosphate hydrolase); GO:0003924 (GTPase activity), GO:0005525 (GTP binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2750  
Description: Protein kinase superfamily protein; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2353  
Description: homeobox-leucine zipper protein ATHB-12-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2731  
Description: disease resistance protein (TIR-NBS-LRR class), putative; IPR000767 (Disease resistance protein), IPR001611 (Leucine-rich repeat), IPR008808 (Powdery mildew resistance protein, RPW8 domain), IPR027417 (P-loop containing nucleoside triphosphate hydrolase); GO:0005515 (protein binding), GO:0006952 (defense response), GO:0043531 (ADP binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2435  
Description: Protein kinase superfamily protein; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 3150  
Description: protein phosphatase 2C 16-like isoform X4 [Glycine max]; IPR001932 (Protein phosphatase 2C (PP2C)-like domain), IPR011009 (Protein kinase-like domain), IPR015655 (Protein phosphatase 2C); GO:0003824 (catalytic activity), GO:0004672 (protein kinase activity), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 320  
Description: threonine--tRNA ligase, mitochondrial-like [Glycine max]; IPR002320 (Threonine-tRNA ligase, class IIa); GO:0000166 (nucleotide binding), GO:0004812 (aminoacyl-tRNA ligase activity), GO:0004829 (threonine-tRNA ligase activity), GO:0005524 (ATP binding), GO:0005737 (cytoplasm), GO:0006418 (tRNA aminoacylation for protein translation), GO:0006435 (threonyl-tRNA aminoacylation)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2105  
Description: Protein kinase superfamily protein; IPR011009 (Protein kinase-like domain), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR016187 (C-type lectin fold); GO:0004672 (protein kinase activity), GO:0004713 (protein tyrosine kinase activity), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation), GO:0030246 (carbohydrate binding)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm3
Annotation: ann1
Length: 1292  
Description: ADP-ribosylation factor GTPase-activating protein AGD12-like isoform X2 [Glycine max]; IPR000008 (C2 domain), IPR001164 (Arf GTPase activating protein); GO:0005515 (protein binding), GO:0008060 (ARF GTPase activator activity), GO:0008270 (zinc ion binding), GO:0032312 (regulation of ARF GTPase activity)
Organism: Cicer arietinum
Strain: CDCFrontier
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2988  
Description: homeobox-leucine zipper protein ATHB-12-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 3543  
Description: receptor-like protein kinase 4; IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1533  
Description: phospholipase A1-IIgamma-like [Glycine max]; IPR000592 (Ribosomal protein S27e), IPR002921 (Lipase, class 3), IPR011332 (Zinc-binding ribosomal protein); GO:0003735 (structural constituent of ribosome), GO:0004806 (triglyceride lipase activity), GO:0005622 (intracellular), GO:0005840 (ribosome), GO:0006412 (translation), GO:0006629 (lipid metabolic process)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 5610  
Description: Protein kinase superfamily protein; IPR011009 (Protein kinase-like domain), IPR015943 (WD40/YVTN repeat-like-containing domain), IPR016024 (Armadillo-type fold); GO:0004672 (protein kinase activity), GO:0004674 (protein serine/threonine kinase activity), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1889  
Description: homeobox-leucine zipper protein ATHB-6-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1595  
Description: homeobox-leucine zipper protein HAT5-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1487  
Description: homeobox-leucine zipper protein ATHB-6-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2015  
Description: homeobox-leucine zipper protein ATHB-12-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1042  
Description: prolyl-tRNA synthetase family protein; IPR004499 (Proline-tRNA ligase, class IIa, archaeal-type); GO:0000166 (nucleotide binding), GO:0004812 (aminoacyl-tRNA ligase activity), GO:0004827 (proline-tRNA ligase activity), GO:0005524 (ATP binding), GO:0005737 (cytoplasm), GO:0006418 (tRNA aminoacylation for protein translation), GO:0006433 (prolyl-tRNA aminoacylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2482  
Description: receptor-like protein kinase 2; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1425  
Description: prolyl-tRNA synthetase family protein; IPR004499 (Proline-tRNA ligase, class IIa, archaeal-type); GO:0000166 (nucleotide binding), GO:0004812 (aminoacyl-tRNA ligase activity), GO:0004827 (proline-tRNA ligase activity), GO:0005524 (ATP binding), GO:0005737 (cytoplasm), GO:0006418 (tRNA aminoacylation for protein translation), GO:0006433 (prolyl-tRNA aminoacylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2600  
Description: Protein kinase superfamily protein; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2877  
Description: receptor-like protein kinase 2; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2323  
Description: WD repeat-containing protein 61-like isoform 1 [Glycine max]; IPR014906 (Pre-mRNA processing factor 4 (PRP4)-like), IPR015943 (WD40/YVTN repeat-like-containing domain), IPR020472 (G-protein beta WD-40 repeat), IPR027106 (U4/U6 small nuclear ribonucleoprotein Prp4); GO:0005515 (protein binding), GO:0008380 (RNA splicing)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 206  
Description: threonine--tRNA ligase, mitochondrial-like [Glycine max]; IPR002320 (Threonine-tRNA ligase, class IIa); GO:0000166 (nucleotide binding), GO:0004812 (aminoacyl-tRNA ligase activity), GO:0004829 (threonine-tRNA ligase activity), GO:0005524 (ATP binding), GO:0005737 (cytoplasm), GO:0006418 (tRNA aminoacylation for protein translation), GO:0006435 (threonyl-tRNA aminoacylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 3409  
Description: receptor-like protein kinase 2; IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1269  
Description: septum-promoting GTP-binding protein 1-like [Glycine max]; IPR003579 (Small GTPase superfamily, Rab type), IPR013684 (Mitochondrial Rho-like), IPR027417 (P-loop containing nucleoside triphosphate hydrolase); GO:0005525 (GTP binding), GO:0005622 (intracellular), GO:0007264 (small GTPase mediated signal transduction), GO:0015031 (protein transport)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 3245  
Description: homeobox-leucine zipper protein HAT5-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2295  
Description: homeobox-leucine zipper protein ATHB-6-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2201  
Description: Protein kinase superfamily protein; IPR011009 (Protein kinase-like domain), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR016187 (C-type lectin fold); GO:0004672 (protein kinase activity), GO:0004713 (protein tyrosine kinase activity), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation), GO:0030246 (carbohydrate binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1714  
Description: homeobox-leucine zipper protein ATHB-6-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 3005  
Description: receptor-like protein kinase 1; IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 5076  
Description: Protein kinase superfamily protein; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2587  
Description: probable plastid-lipid-associated protein 14, chloroplastic-like isoform X3 [Glycine max]; IPR006843 (Plastid lipid-associated protein/fibrillin conserved domain), IPR011009 (Protein kinase-like domain); GO:0004672 (protein kinase activity), GO:0005198 (structural molecule activity), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation), GO:0009507 (chloroplast)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2275  
Description: signal recognition particle subunit SRP68-like [Glycine max]; IPR026258 (Signal recognition particle subunit SRP68); GO:0005047 (signal recognition particle binding), GO:0006614 (SRP-dependent cotranslational protein targeting to membrane), GO:0008312 (7S RNA binding), GO:0030942 (endoplasmic reticulum signal peptide binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2133  
Description: RNA-binding protein 39-like isoform X1 [Glycine max]; IPR006529 (U2 snRNP auxilliary factor, large subunit, splicing factor), IPR012677 (Nucleotide-binding, alpha-beta plait); GO:0000166 (nucleotide binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0005634 (nucleus), GO:0006397 (mRNA processing)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 8810  
Description: uncharacterized protein LOC100802419 isoform X4 [Glycine max]; IPR011990 (Tetratricopeptide-like helical), IPR014016 (UvrD-like Helicase, ATP-binding domain), IPR014017 (DNA helicase, UvrD-like, C-terminal), IPR027417 (P-loop containing nucleoside triphosphate hydrolase); GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0016787 (hydrolase activity)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 3404  
Description: receptor-like protein kinase 2; IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 5383  
Description: DNA repair protein UVH3-like isoform X1 [Glycine max]; IPR006084 (XPG/Rad2 endonuclease); GO:0003677 (DNA binding), GO:0003697 (single-stranded DNA binding), GO:0003824 (catalytic activity), GO:0004518 (nuclease activity), GO:0004519 (endonuclease activity), GO:0005634 (nucleus), GO:0006281 (DNA repair), GO:0006289 (nucleotide-excision repair)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 5306  
Description: chromodomain-helicase-DNA-binding protein 1-like isoform X2 [Glycine max]; IPR000330 (SNF2-related), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR016197 (Chromo domain-like), IPR027417 (P-loop containing nucleoside triphosphate hydrolase); GO:0003677 (DNA binding), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0008270 (zinc ion binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 10829  
Description: chromodomain-helicase-DNA-binding protein 1-like isoform X2 [Glycine max]; IPR000330 (SNF2-related), IPR001650 (Helicase, C-terminal), IPR014012 (Helicase/SANT-associated, DNA binding), IPR027417 (P-loop containing nucleoside triphosphate hydrolase); GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0004386 (helicase activity), GO:0005524 (ATP binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1984  
Description: trihelix transcription factor GT-1-like isoform 1 [Glycine max]; IPR009057 (Homeodomain-like), IPR027775 (C2H2- zinc finger protein family); GO:0003677 (DNA binding), GO:0003682 (chromatin binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1607  
Description: dual specificity protein phosphatase 1-like [Glycine max]; IPR000340 (Dual specificity phosphatase, catalytic domain), IPR024950 (Dual specificity phosphatase); GO:0004725 (protein tyrosine phosphatase activity), GO:0006470 (protein dephosphorylation), GO:0008138 (protein tyrosine/serine/threonine phosphatase activity), GO:0016311 (dephosphorylation), GO:0016791 (phosphatase activity)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2337  
Description: arginine--tRNA ligase, cytoplasmic-like [Glycine max]; IPR001278 (Arginine-tRNA ligase, class Ia); GO:0000166 (nucleotide binding), GO:0004812 (aminoacyl-tRNA ligase activity), GO:0004814 (arginine-tRNA ligase activity), GO:0005524 (ATP binding), GO:0005737 (cytoplasm), GO:0006418 (tRNA aminoacylation for protein translation), GO:0006420 (arginyl-tRNA aminoacylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 3137  
Description: Protein kinase family protein; IPR001611 (Leucine-rich repeat), IPR011009 (Protein kinase-like domain), IPR013210 (Leucine-rich repeat-containing N-terminal, type 2), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup); GO:0004672 (protein kinase activity), GO:0005515 (protein binding), GO:0005524 (ATP binding), GO:0006468 (protein phosphorylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2036  
Description: zinc finger CCCH domain-containing protein 69-like isoform X1 [Glycine max]; IPR000571 (Zinc finger, CCCH-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR026290 (Putative E3 ubiquitin-protein ligase, makorin-related); GO:0005515 (protein binding), GO:0008270 (zinc ion binding), GO:0046872 (metal ion binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2381  
Description: arginine--tRNA ligase, cytoplasmic-like [Glycine max]; IPR001278 (Arginine-tRNA ligase, class Ia); GO:0000166 (nucleotide binding), GO:0004812 (aminoacyl-tRNA ligase activity), GO:0004814 (arginine-tRNA ligase activity), GO:0005524 (ATP binding), GO:0005737 (cytoplasm), GO:0006418 (tRNA aminoacylation for protein translation), GO:0006420 (arginyl-tRNA aminoacylation)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1712  
Description: homeobox-leucine zipper protein ATHB-20-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 1517  
Description: homeobox-leucine zipper protein ATHB-13-like [Glycine max]; IPR003106 (Leucine zipper, homeobox-associated), IPR009057 (Homeodomain-like); GO:0000976 (transcription regulatory region sequence-specific DNA binding), GO:0003677 (DNA binding), GO:0003700 (sequence-specific DNA binding transcription factor activity), GO:0005634 (nucleus), GO:0043565 (sequence-specific DNA binding)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm1
Annotation: ann1
Length: 2655  
Description: ADP-ribosylation factor GTPase-activating protein AGD12 isoform X1 [Glycine max]; IPR000008 (C2 domain), IPR001164 (Arf GTPase activating protein); GO:0005515 (protein binding), GO:0008060 (ARF GTPase activator activity), GO:0008270 (zinc ion binding), GO:0032312 (regulation of ARF GTPase activity)
Organism: Cicer echinospermum
Strain: S2Drd065
mRNA
Assembly: gnm3
Annotation: ann1
Length: 2142  
Description: RNA-binding protein 39-like isoform X1 [Glycine max]; IPR006529 (U2 snRNP auxilliary factor, large subunit, splicing factor), IPR012677 (Nucleotide-binding, alpha-beta plait); GO:0000166 (nucleotide binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0005634 (nucleus), GO:0006397 (mRNA processing)
Organism: Cicer arietinum
Strain: CDCFrontier
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