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Search results 8501 to 8600 out of 30763 for seed protein

Category restricted to ProteinDomain (x)

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Categories

Category: ProteinDomain
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Type Details Score
Protein Domain
IPR006340
Name: Protein of unknown function DUF436
Type: Family
Description: Members of this family are uncharacterised proteins predominantly found in Firmicutes in no more than one copy per genome.
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Protein Domain
IPR045949
Name: Protein of unknown function DUF6369
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000728) is described by MIBiG as an example of the following biosynthetic class, saccharide, in particular the capsular polysaccharide biosynthetic gene cluster from Klebsiella pneumoniae subsp. ozaenae [ ].
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Protein Domain
IPR045947
Name: Protein of unknown function DUF6367
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001053) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the tubulysin A biosynthetic gene cluster from Archangium disciforme [ ].
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Protein Domain
IPR045948
Name: Protein of unknown function DUF6368
Type: Family
Description: This BGC (BGC0001740) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the phthoxazolin biosynthetic gene cluster from Streptomyces avermitilis [ ].
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Protein Domain
IPR045945
Name: Protein of unknown function DUF6365
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001960) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the hiroshidine biosynthetic gene cluster from Streptomyces hiroshimensis [ ].
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Protein Domain
IPR045946
Name: Protein of unknown function DUF6366
Type: Family
Description: This family of proteins is functionally uncharacterised. Proteins in this family are found predominantly in Firmicutes and contain the RE/K and GW conserved motifs.
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Protein Domain
IPR045944
Name: Protein of unknown function DUF6364
Type: Family
Description: This family of uncharacterised proteins is found mainly in bacteria. Proteins in this family seem to belong to the toxin-antitoxin system. They are likely to contain a ribbon-helix-helix DNA-binding motif.
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Protein Domain
IPR045941
Name: Protein of unknown function DUF6361
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found mainly in bacteria.
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Protein Domain
IPR045940
Name: Protein of unknown function DUF6360
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is predominantly found in archaea.
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Protein Domain
IPR045938
Name: Protein of unknown function DUF6358
Type: Family
Description: This family of integral membrane proteins is functionally uncharacterised. This family of proteins is predominantly found in Bacteroidetes. There are two conserved sequence motifs: FILN and VVLIYLK. This family is related to PF17259.
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Protein Domain
IPR045936
Name: Protein of unknown function DUF6356
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found mostly in bacteria. Proteins in this family are typically between 71 and 88 amino acids in length. There are two conserved sequence motifs: KTGS and RMV.
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Protein Domain
IPR045937
Name: Protein of unknown function DUF6357
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000368) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide), in particular the streptobactin biosynthetic gene cluster from Streptomyces sp. ATCC 700974 [ ].
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Protein Domain
IPR045934
Name: Protein of unknown function DUF6354
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001735) is described by MIBiG as an example of the following biosynthetic class, other (unspecified), in particular the pentostatine biosynthetic gene cluster from Streptomyces antibioticus [ ].
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Protein Domain
IPR045935
Name: Protein of unknown function DUF6355
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001807) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the totopotensamide A biosynthetic gene cluster from Streptomyces pactum [ ]. This family appears to be predominantly present in Actinobacteria.
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Protein Domain
IPR045932
Name: Protein of unknown function DUF6352
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found mainly in Proteobacteria.
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Protein Domain
IPR045933
Name: Protein of unknown function DUF6353
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria and viruses.
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Protein Domain
IPR045930
Name: Protein of unknown function DUF6349
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000703) is described by MIBiG as an example of the following biosynthetic class, saccharide, in particular the kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus [ ].
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Protein Domain
IPR045931
Name: Protein of unknown function DUF6350
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found mainly in Actinobacteria.
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Protein Domain
IPR021972
Name: Parvovirus non-structural protein 1, C-terminal
Type: Domain
Description: Parvoviruses are some of the smallest viruses containing linear, non-segmented single-stranded DNA genomes, with an average genome size of 5000 nucleotides. Parvoviruses have been described that infect a wide range of invertebrates and vertebrates and are well known for causing enteric disease in mammals. Genomes contain two large ORFs: NS1 and VP1; other ORFs are found in some sub-types and different gene products can arise from splice variants and the use of different start codons [ , ].NS1 protein is essential for viral life cycle stages, including DNA replication, trans-regulation of the two viral promoters, and modulation of heterologous promoters. It exhibits DNA binding, endonuclease and helicase activities and is a major contributor to the toxic effect on host cells [ ]. This is the transactivation domain of the parvovirus NS1 protein, located immediately C-terminal to the helicase [, ].
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Protein Domain
IPR021974
Name: Protein of unknown function DUF3581
Type: Family
Description: This family consists of uncharacterised bacterial proteins.
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Protein Domain
IPR021978
Name: Protein of unknown function DUF3583
Type: Family
Description: This domain is found in eukaryotes, and is typically between 302 and 338 amino acids in length. It is found in association with and . Most members are promyelocytic leukemia proteins, and this family lies towards the C terminus. Proteins containing this domain include PML protein from mammals. PML (promyelocytic leukaemia) functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms [ ].
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Protein Domain
IPR021979
Name: Protein of unknown function DUF3584
Type: Family
Description: This family consist of uncharacterised bacterial and archaeal proteins.
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Protein Domain
IPR045929
Name: Protein of unknown function DUF6348
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0002011) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the ansacarbamitocin A biosynthetic gene cluster from Amycolatopsis alba DSM 44262. This family appears to be predominantly found in bacteria.
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Protein Domain
IPR045927
Name: Protein of unknown function DUF6346
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000223) is described by MIBiG as an example of the following biosynthetic class, polyketide, rabelomycin biosynthetic gene cluster from uncultured bacterium BAC AB649/1850 [ ]. This family appears to be predominantly found in Actinobacteria.
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Protein Domain
IPR045928
Name: Protein of unknown function DUF6347
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001130) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the fabclavine Ia biosynthetic gene cluster from Xenorhabdus budapestensis [ ].
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Protein Domain
IPR045925
Name: Protein of unknown function DUF6344
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000843) is described by MIBiG as an example of the following biosynthetic class, other (unspecified), in particular the alanylclavam biosynthetic gene cluster from Streptomyces clavuligerus ATCC 27064 [ , ]. This family appears to be predominantly found in Actinobacteria.
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Protein Domain
IPR045926
Name: Protein of unknown function DUF6345
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000703) is described by MIBiG as an example of the following biosynthetic class, saccharide, in particular the kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus [ ]. This family appears to be predominantly found in bacteria and archaea.
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Protein Domain
IPR045923
Name: Protein of unknown function DUF6342
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001877) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the cyphomycin biosynthetic gene cluster from Streptomyces sp. ISID311 [ ].
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Protein Domain
IPR045924
Name: Protein of unknown function DUF6343
Type: Family
Description: This entry represents a member of a bacterial biosynthetic gene cluster (BGC). This BGC (BGC0001558) is described by MIBiG as an example of the following biosynthetic class, polyketide, in particular the cosmomycin C biosynthetic gene cluster from Streptomyces sp. CNT302 [ ]. This family appears to be predominantly found in Actinobacteria.
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Protein Domain
IPR045921
Name: Protein of unknown function DUF6340
Type: Family
Description: This family of proteins is mainly found in bacteria and it is functionally uncharacterised. Members in this family are about 350 amino acids in length and are likely to contain tetratricopeptide (TRP) repeats.
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Protein Domain
IPR045922
Name: Protein of unknown function DUF6341
Type: Family
Description: This family of uncharacterised proteins is found mainly in bacteria. Proteins in this family are approximately 70 amino acids in length. There are two conserved sequence motifs, WIF and YW. Most members are though to be Uracil phosphoribosyltransferases.
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Protein Domain
IPR021960
Name: Protein of unknown function DUF3577
Type: Family
Description: This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 143 to 307 amino acids in length.
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Protein Domain
IPR045920
Name: Protein of unknown function DUF6339
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 247 and 267 amino acids in length.
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Protein Domain
IPR021969
Name: Protein of unknown function DUF3579
Type: Family
Description: This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 98 to 126 amino acids in length. This protein has a conserved FRP sequence motif.
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Protein Domain
IPR045918
Name: Protein of unknown function DUF6337
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000791) is described by MIBiG as an example of the following biosynthetic class, saccharide, in particular the O-antigen biosynthetic gene cluster from Cronobacter sakazakii [ ].
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Protein Domain
IPR045919
Name: Protein of unknown function DUF6338
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001593) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide), in particular the ficellomycin biosynthetic gene cluster from Streptomyces ficellus [ ].
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Protein Domain
IPR006335
Name: Glutathione biosynthesis bifunctional protein GshAB
Type: Family
Description: This entry represents a family with an N-terminal region similar to proteobacterial glutamate-cysteine ligase (gamma-glutamylcysteine synthetase). The C-terminal region is homologous to cyanophycin synthetase of cyanobacteria, and to D-alanine-D-alanine ligases [ ]. Cyanophycin is a storage molecule composed of arginine, aspartic acid, and some glutamic acid. Members of this family are found in Listeria and Enterococcus, Gram-positive lineages in which glutathione is produced [], and in proteobacterium Pasteurella multocida.
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Protein Domain
IPR021951
Name: Protein of unknown function DUF3567
Type: Family
Description: This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are about 90 amino acids in length. This protein has a conserved EIVDK sequence motif.
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Protein Domain
IPR021953
Name: Protein of unknown function DUF3570
Type: Family
Description: This family of bacterial proteins is functionally uncharacterised. Proteins in this family are typically between 396 to 444 amino acids in length. Members in this family contain the conserved [S/T]GA[S/T]motif and are flavinylation substrates for ApbE, which suggests that they may be involved in extra cytosolic redox activities [ ].
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Protein Domain
IPR021955
Name: Protein of unknown function DUF3572
Type: Family
Description: This family of proteins is functionally uncharacterised. Proteins in this family are about 100 amino acids in length and are found in bacteria.
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Protein Domain
IPR021956
Name: Protein of unknown function DUF3573
Type: Family
Description: This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 372 to 530 amino acids in length.
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Protein Domain
IPR021958
Name: Protein of unknown function DUF3575
Type: Family
Description: This family of proteins are functionally uncharacterised. This family is only found in bacteria. Proteins in this family are typically between 187 to 236 amino acids in length.
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Protein Domain
IPR021959
Name: Protein of unknown function DUF3576
Type: Family
Description: This presumed domain is functionally uncharacterised. This domain is found in bacteria. This domain is about 100 amino acids in length. This domain has a single completely conserved residue G that may be functionally important.
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Protein Domain
IPR006144
Name: Secretion protein HlyD, conserved site
Type: Conserved_site
Description: Gram-negative bacteria produce a number of proteins which are secreted into the growth medium by a mechanism that does not require a cleaved N-terminalsignal sequence. These proteins, while having different functions, require the help of two or more proteins for their secretion across the cell envelope. The secretion proteins are evolutionary related and consist of from 390 to 480 amino acid residues. They seem to be anchored in the inner membrane by a N-terminaltransmembrane region. The C-terminal section of these proteins is the best conserved region.
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Protein Domain
IPR045749
Name: Protein of unknown function DUF6090
Type: Family
Description: This family of proteins is functionally uncharacterised. Proteins in this family are primarily found in Bacteroidetes.
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Protein Domain
IPR021782
Name: Protein of unknown function DUF3347
Type: Domain
Description: This entry represents a functionally uncharacterised domain found in bacterial proteins.
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Protein Domain
IPR021783
Name: Protein of unknown function DUF3348
Type: Family
Description: This family of proteins are functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 244 to 323 amino acids in length.
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Protein Domain
IPR021784
Name: Protein of unknown function DUF3349
Type: Family
Description: This family of proteins are functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 99 to 124 amino acids in length. According to literature, the DUF3349 proteins are predicted to be good drug targets because they are predominantly in the Mycobacterium and Rhodococcus bacterial species [ ].
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Protein Domain
IPR021787
Name: Protein of unknown function DUF3352
Type: Family
Description: This family of proteins are functionally uncharacterised. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 538 to 575 amino acids in length.
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Protein Domain
IPR045740
Name: BTB/POZ domain-containing protein KCTD4, C-terminal
Type: Domain
Description: This entry represents the C-terminal region of BTB/POZ domain-containing protein KCTD4. This domain is highly variable among the BTB domain-containing KCTD proteins and it has been proposed that it could play a role in binding or recruiting diverse protein targets involved in different cellular processes, such us ubiquitination, cell proliferation or control of G-protein coupled receptors, among others [ , ].
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Protein Domain
IPR045738
Name: Protein of unknown function DUF6088
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found primarily in bacteria. This family appears to be distantly related to AbiEi antitoxin ( ) suggesting proteins in this family may be an antitoxin component of a toxin/antitoxin system.
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Protein Domain
IPR021770
Name: Protein of unknown function DUF3335
Type: Family
Description: This family of proteins are functionally uncharacterised. This family is only found in bacteria. This presumed domain is typically between 226 to 230 amino acids in length.
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Protein Domain
IPR045732
Name: Protein of unknown function DUF6086
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000721) is described by MIBiG as an example of the following biosynthetic class, saccharide. This family includes a protein from the tobramycin biosynthetic gene cluster from Streptoalloteichus tenebrarius and appears to be predominantly found in Actinobacteria [ ].
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Protein Domain
IPR045733
Name: Protein of unknown function DUF6087
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000703) is described by MIBiG as an example of the following biosynthetic class, saccharide. This family includes a protein from the kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus [ ].
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Protein Domain
IPR021774
Name: Cytohesin Ubiquitin Protein Inducing Domain
Type: Domain
Description: This entry represents a domain named CUPID (Cytohesin Ubiquitin Protein Inducing Domain) that is found in animal proteins. It is found towards the N-terminal end of Innate immunity activator protein (INAVA, Innate Immune Activator), a risk factor for the chronic inflammatory bowel diseases (IBD). Mice lacking the protein show defects in intestinal barrier integrity at steady state and greater susceptibility to mucosal infection. CUPID is also found towards the N-terminal end of Coiled-coil domain-containing protein 120 (CC120) and C-terminal to the FERM domain in FERM domain-containing protein 4A/B (FRM4A/B), which are implicated in neurite outgrowth, and in human cancer, Alzheimer's, celiac, and heart disease. All appear to bind the ARF-GEF (guanine nucleotide-exchange factors) cytohesin family members, such as proteins (ARF 1-4), which regulate cell membrane and F-actin dynamics. INAVA-CUPID binds cytohesin 2 (also known as ARNO), targets the molecule to lateral membranes of epithelial monolayers, and enables ARNO to affect F-actin assembly that underlies cell-cell junctions and barrier function. In the case of inflammatory signalling, ARNO can coordinate CUPID function by binding and inhibiting CUPID activity of acting as an enhancer of TRAF6 dependent polyubiquitination. In other words, ARNO acts as a negative-regulator of inflammatory responses. In summary, INAVA-CUPID exhibits dual functions, coordinated directly by ARNO, that bridge epithelial barrier function with extracellular signals and inflammation [ , , ].
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Protein Domain
IPR045730
Name: Protein of unknown function DUF6084
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001065) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family includes a protein from the herboxidiene biosynthetic gene cluster from Streptomyces chromofuscus and appears to be predominantly found in Actinobacteria [ ].
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Protein Domain
IPR045731
Name: Protein of unknown function DUF6085
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001905) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family includes a protein from the violapyrone B biosynthetic gene cluster from Streptomyces somaliensis and appears to be predominantly found in Actinobacteria and Caudovirales bacteriophages [ ].
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Protein Domain
IPR021779
Name: Protein of unknown function DUF3344
Type: Family
Description: This family of proteins are functionally uncharacterised. This protein is found in bacteria and archaea. Proteins in this family are typically between 367 to 1857 amino acids in length.
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Protein Domain
IPR045729
Name: Protein of unknown function DUF6083
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC00001735) is described by MIBiG as an example of the following biosynthetic class, other. This family includes a protein from the pentostatine biosynthetic gene cluster from Streptomyces antibioticus and appears to be predominantly found in Streptomyces [ ].
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Protein Domain
IPR045727
Name: Protein of unknown function DUF6081
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001964) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family includes a protein from the alkylpyrone-407 biosynthetic gene cluster from Cystobacterineae bacterium [ ].
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Protein Domain
IPR045728
Name: Protein of unknown function DUF6082
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000703) is described by MIBiG as an example of the following biosynthetic class, saccharide. This family includes a protein from the kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus and appears to be predominantly found in Actinobacteria [ ].
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Protein Domain
IPR045725
Name: Protein of unknown function DUF6079
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria and archaea. Some members contain a P-loop domain at their N terminus.
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Protein Domain
IPR045726
Name: Protein of unknown function DUF6080
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria.
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Protein Domain
IPR045723
Name: Protein of unknown function DUF6077
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria.
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Protein Domain
IPR045724
Name: Protein of unknown function DUF6078
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in Bacteroidetes bacteria. This family contains 4 conserved cysteines towards the N terminus which may form a zinc-binding motif.
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Protein Domain
IPR045721
Name: Protein of unknown function DUF6075
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found primarily in Firmicute bacteria. Proteins in this family are typically between 130 and 155 amino acids in length. There is a conserved AFNL sequence motif.
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Protein Domain
IPR021762
Name: Protein of unknown function DUF3325
Type: Family
Description: This family of short proteins are functionally uncharacterised. This family is restricted to Alpha-, Beta- and Gamma-proteobacteria.
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Protein Domain
IPR045722
Name: Protein of unknown function DUF6076
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is primarily found in Firmicute bacteria. These proteins contain 4 conserved cysteines suggestive of a zinc-binding motif.
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Protein Domain
IPR045720
Name: Protein of unknown function DUF6074
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001765) is described by MIBiG as an example of the following biosynthetic class, saccharide. This family includes a protein from the salecan biosynthetic gene cluster from Agrobacterium tumefaciens and appears to be predominantly found in Rhizobiales [].
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Protein Domain
IPR021766
Name: Phosphate regulon sensor protein PhoR
Type: Family
Description: PhoR is a member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR is the bifunctional histidine autokinase/phospho-PhoB phosphatase that donates a phosphoryl group to PhoB when environmental Pi is limiting and removes the phosphoryl group from phosphorylated PhoB (PhoB~P) when environmental Pi is abundant [ ].
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Protein Domain
IPR021768
Name: Protein of unknown function DUF3332
Type: Family
Description: This family of proteins is functionally uncharacterised.
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Protein Domain
IPR021769
Name: Protein of unknown function DUF3331
Type: Family
Description: This family of proteins are functionally uncharacterised. This family is only found in bacteria. Proteins in this family vary in length from 96 to 160 amino acids.
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Protein Domain
IPR033743
Name: Effector protein HopAB, Pto-binding domain
Type: Domain
Description: HopAB family members are type III effector proteins that are secreted by the plant pathogen Pseudomonas syringae into the host plant to inhibit its immune system and facilitate the spread of the pathogen [ ]. AvrPtoB, also called HopAB3, is the best studied member of the family. It suppresses host basal defenses by interfering with PAMP (pathogen-associated molecular signature)-triggered immunity (PTI) through binding and inhibiting BAK1, a kinase which serves to activate defense signaling []. It also recognizes the kinase Pto to activate effector-triggered immunity (ETI) [].AvrPtoB contains an N-terminal region that contains two kinase-interacting domains (KID) and a C-terminal E3 ligase domain. The first KID recognizes the PTI-associated kinase Bti9 as well as Pto, and is referred to as the Pto-binding domain (PID). The second KID interacts with BAK1 and FLS2, which are leucine-rich repeat-containing receptor-like kinases, and is called the BAK1-interacting domain (BID) [ , ] . The family member HopPmaL is shorter and lacks the C-terminal E3 ligase domain [].This entry represents the Pto-binding domain.
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Protein Domain
IPR045718
Name: Protein of unknown function DUF6072
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000967) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide. This family includes a protein from the calyculin A biosynthetic gene cluster from uncultured Candidatus Entotheonella sp. and appears to be predominantly found in bacteria.
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Protein Domain
IPR045719
Name: Protein of unknown function DUF6073
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001804) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family includes a protein from the tiancimycin biosynthetic gene cluster from Streptomyces sp. CB03234 and appears to be predominantly found in bacteria [ ].
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Protein Domain
IPR045714
Name: Protein of unknown function DUF6070
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in Firmicutes. There are two conserved sequence motifs: PEV and DGT.
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Protein Domain
IPR045715
Name: Protein of unknown function DUF6071
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001065) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family contains a protein from the herboxidiene biosynthetic gene cluster from Streptomyces chromofuscus [ ].
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Protein Domain
IPR045712
Name: Protein of unknown function DUF6068
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001902) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide. This family includes a protein from the bengamide biosynthetic gene cluster from Myxococcus virescens and appears to be predominantly found in Cystobacterineae [ ].
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Protein Domain
IPR045713
Name: Protein of unknown function DUF6069
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001769) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family includes a protein from the family saquayamycin A biosynthetic gene cluster from Streptomyces sp. and appears to be predominantly found in Actinobacteria [ ].
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Protein Domain
IPR045710
Name: Protein of unknown function DUF6066
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001418) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide. This family includes a protein from the myxochromide D biosynthetic gene cluster from Hyalangium minutum and appears to be predominantly found in Cystobacterineae [ ].
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Protein Domain
IPR021751
Name: Protein of unknown function DUF3318
Type: Family
Description: This is a bacterial family of uncharacterised proteins.
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Protein Domain
IPR021753
Name: Protein of unknown function DUF3319
Type: Family
Description: This is a family of short bacterial proteins, a few of which are annotated as being minor tail protein. Otherwise the function is unknown.
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Protein Domain
IPR045789
Name: Protein inscuteable homologue, C-terminal domain
Type: Domain
Description: This entry represents the C-terminal region of protein Inscuteable (Insc) containing four putative armadillo repeats and the conserved extreme C-terminal tetrapeptide Glu-Ser-Phe-Val which is in agreement with the class I PDZ-binding motif X-Ser/Thr-X-/ (X and / are unspecified and hydrophobic residues, respectively). Insc functions as an adaptor protein that binds simultaneously with Partner of Insc (Pins, consisting of alpha subunit (Ga) of heterotrimeric G proteins and its guanine nucleotide dissociation inhibitor) and Par3 (PDZ-containing proteins) to regulate their apical localisation in neuroblasts, which is required for the correct execution of the asymmetric division [ , ].
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Protein Domain
IPR043124
Name: DNA terminal protein Gp3, C-terminal
Type: Homologous_superfamily
Description: The DNA terminal protein Gp3, found in a number of Bacillus phages, is linked to the 5' ends of both strands of the genome through a phosphodiester bond between the β-hydroxyl group of a serine residue and the 5'-phosphate of the terminal deoxyadenylate. This protein is essential for DNA replication and is involved in the priming of DNA elongation [ ].This superfamily entry represents the C-terminal priming domain of the DNA terminal protein GP3 sequences from Phi-29 like bacteriophages. In the transition from the initiation to the elongation phases, the priming domain of terminal protein moves out of the active site as polymerase elongates the primer strand. The terminal protein dissociates from the polymerase after the incorporation of approximately six nucleotides [ ].This domain is a four-helix bundle with a left turning up-down-up-down topology. Serine-232, which provides the priming hydroxyl group for DNA synthesis, lies in a loop at the end of the domain closest to the active site of the DNA polymerase [ ].
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Protein Domain
IPR045781
Name: Saxitoxin biosynthesis operon protein SxtJ
Type: Family
Description: This family of integral membrane proteins is functionally uncharacterised. It is found in cyanobacterial Saxitoxin biosynthesis operon []. This family of proteins is found in bacteria.
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Protein Domain
IPR045780
Name: Protein of unknown function DUF6206
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001063) is described by MIBiG as an example of the polyketide and NRP (non-ribosomal peptide) biosynthetic classes. It includes a member from the undecylprodigiosin biosynthetic gene cluster from Streptomyces coelicolor A3(2) [ , ]. This family appears to be predominantly present in bacteria.
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Protein Domain
IPR045778
Name: Protein of unknown function DUF6204
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001070) is described by MIBiG as an example of the NRP (non-ribosomal peptide) and polyketide biosynthetic classes. It includes a member from the kirromycin biosynthetic gene cluster from Streptomyces collinus Tu 365 [ , ]. This family appears to be predominantly found in Actinobacteria.
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Protein Domain
IPR045779
Name: Protein of unknown function DUF6205
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000078) is described by MIBiG as an example of the polyketide biosynthetic class. It includes a member from the incednine biosynthetic gene cluster from Streptomyces sp. ML694-90F3 [ ].
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Protein Domain
IPR045776
Name: Protein of unknown function DUF6202
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000877) is described by MIBiG as an example of the following biosynthetic class, other (unspecified). It includes a member from the polyoxin A biosynthetic gene cluster from Streptomyces cacaoi subsp. asoensis [ , ].
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Protein Domain
IPR043116
Name: Outer capsid protein VP9, N-terminal
Type: Homologous_superfamily
Description: VP9 is a spike-forming protein that mediates virion attachment to the host cell receptors and plays a major role in cell penetration [ ]. This superfamily represents the N-terminal domain of the VP9 protein. Structurally, this domain has a left-handed superhelix made up of three alpha helices. These helices interact with sister helices on other VP9 monomers to form a VP9 trimer. This VP9 trimer is then expressed on the surface of the virus particle, and implicated in receptor binding interactions.
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Protein Domain
IPR045777
Name: Protein of unknown function DUF6203
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001944) is described by MIBiG as an example of the polyketide biosynthetic class. It includes a member from the funisamine biosynthetic gene cluster from Streptosporangium sp. [ ].
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Protein Domain
IPR045775
Name: Protein of unknown function DUF6207
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001709) is described by MIBiG as an example of the polyketide biosynthetic class. It includes a member from the nystatin biosynthetic gene cluster from Streptomyces albulus [ ]. This family appears to be predominantly found in Actinobacteria.
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Protein Domain
IPR045772
Name: Protein of unknown function DUF6225
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000896) is described by MIBiG as an example of the following biosynthetic class, other (unspecified). It includes a member from the cycloserine biosynthetic gene cluster from Streptomyces lavendulae subsp. lavendulae [ ].
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Protein Domain
IPR045773
Name: Protein of unknown function DUF6226
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000223) is described by MIBiG as an example of the polyketide biosynthetic class. It includes a member from the rabelomycin biosynthetic gene cluster from uncultured bacterium BAC AB649/1850 [ ]. This family appears to be predominantly found in Actinobacteria.
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Protein Domain
IPR045770
Name: Protein of unknown function DUF6223
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001848) is described by MIBiG as an example of the following biosynthetic class, other (unspecified). It includes a member from the diazaquinomycin H biosynthetic gene cluster from Micromonospora sp. B006 [ ]. This family appears to be predominantly found in bacteria.
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Protein Domain
IPR045771
Name: Protein of unknown function DUF6224
Type: Family
Description: This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000084) is described by MIBiG as an example of the polyketide biosynthetic class. It includes a member from the laidlomycin biosynthetic gene cluster from Streptomyces sp. CS684 [ ].
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Protein Domain
IPR031121
Name: KH domain containing protein RIK/BLOM7
Type: Family
Description: This entry represents a group of KH domain containing proteins from eukaryotes, including RIK (rough sheath 2-interacting KH domain) from plants and BLOM7 (also known as KH homology domain-containing protein 4) from animals. RIK1 interacts with rough sheath2 (RS2), which is a myb domain protein required to repress knox genes during leaf development [ ]. BLOM7 is a RNA-binding protein involved in pre-mRNA splicing []. It has been shown to interact with SNEV (Prp19/Pso4), a splicing factor [].
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Protein Domain
IPR045767
Name: Protein of unknown function DUF6134
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found predominantly in Proteobacteria and Bacteroidetes. Proteins in this family are typically between 210 and 241 amino acids in length.
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Protein Domain
IPR045765
Name: Protein of unknown function DUF6133
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is mainly found in Firmicutes. Proteins in this family are typically between 73 and 87 amino acids in length. There are two conserved sequence motifs: KIL and LLLAGLY.
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Protein Domain
IPR045764
Name: Protein of unknown function DUF6132
Type: Family
Description: This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria. Proteins in this family are typically between 58 and 74 amino acids in length.
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