Protein Domain : Type VI secretion system, RhsGE-associated Vgr protein IPR006533

Type  Family
Description  Type VI secretion system (T6SS) appears to be confined to Proteobacteria. It is important for bacterial pathogenesis, but it is also found in non-pathogenic bacteria, suggesting that T6SS involvement is not limited to virulence [ ]. T6SS was identified in Vibrio cholerae [] and Pseudomonas aeruginosa [], and exports Hcp (Haemolysin-Coregulated Protein) and a class of proteins named Vgr (Val-Gly Repeats). In addition to Vgr and Hcp proteins, T6SS is characterised by the presence of an AAA+ Clp-like ATPase and of two additional genes icmF and dotU, encoding homologues of T4SS stabilising proteins []. This entry represent the Vgr family of proteins, associated with some classes of Rhs elements (Rhs classes G and E). Rsh (rearrangement hot-spot) elements are repetitious sequences identified in certain Escherichia coli strains [ , ].
Short Name  T6SS_Vgr_RhsGE

1 Child Features

0 Gene Families

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