Protein Domain : SAPK-interacting protein 1, Pleckstrin-homology domain IPR031313

Type  Domain
Description  This entry represents a pleckstrin-homology domain found at the C terminus of Stress-activated map kinase interacting 1 (Sin1) and its Saccharomyces cerevisiae orthologue Avo1. It is conserved from yeast to humans. PH-domains are involved in intracellular signalling or as constituents of the cytoskeleton. Sin1 plays an essential role in signal transduction, and the PH domain is involved in lipid and membrane binding [ ].
Short Name  Sin1_PH_dom
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