LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | Coronavirus non-structural protein 2 (NSP2) is encoded by ORF1a/1ab and proteolytically released from the pp1a/1ab polyprotein. Viral-host protein interaction studies in SARS-CoV and SARS-CoV-2 found that this protein could interact with several host proteins, including prohibitin 1 (PHB1) and PHB2, which are implicated in a number of cellular functions, including cellular migration, differentiation and apoptosis [ , ]. NSP2 structure from SARS-CoV-2 has been recently solved and revealed that it has three zinc fingers, which may be involved in binding nucleic acids and regulating intracellular signalling pathways []. NSP2 has been pointed as an interesting target to develop anti-SARS-COV-2 therapies as it may play important roles during viral infection.This domain is found at the C-terminal of NSP2 in alpha and betacoronaviruses. It is found in two copies in some viral NSP2 proteins. |
| Short Name | CoV_NSP2_C |
