Protein Domain : DNA replication complex GINS protein SLD5, C-terminal IPR031633

Type  Domain
Description  DNA replication complex GINS protein SLD5 is a component of the GINS tetrameric protein complex, which is involved in both initiation and elongation stages of eukaryotic chromosome replication [ , , , ]. It is essential for the maintenance of genomic integrity, GINS plays a central role in coordinating DNA replication with cell cycle checkpoints and is involved in cell growth. It has been associated with NK cell deficiency and neutropenia [, , ].This entry represents the C-terminal domain of SLD5. This region is important in the assembly of the GINS complex.
Short Name  SLD5_C
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