Protein Domain : STI1/HOP, DP domain IPR041243

Type	Domain
Description	This entry corresponds to the Asp/Pro-rich domains (DP) of STI1/HOP and similar proteins [ ], including TIC40, a co-chaperone during protein import into chloroplasts []. STI1/HOP proteins are cochaperones that belong to the foldosome, a system consisting in Hsp70 and Hsp90 chaperones. STI1/HOP acts as an adapter protein capable of transferring client proteins from the first to the second molecular chaperone []. This domain is found in two copies in STI1, named DP1 and DP2 [, , ], while in others is present in one copy, such as Hsp70-Hsp90 organising protein from P. falciparum. This domain (and specifically DP2 from STI1), is involved in client activation [].
Short Name	STI1/HOP_DP