v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | Secreted frizzled-related proteins (Sfrps) are soluble proteins containing an Netrin (NTR) domain C-terminal to a cysteine-rich Frizzled domain [ ]. They show diverse functions and are thought to work in Wnt signaling indirectly, as modulators or antagonists by binding Wnt ligands, and directly, via the Wnt receptor, Frizzled [].SFRP3 (also known as FRZB) regulates chondrocyte maturation and long bone development [ ]. It is an antagonist of Wnt8 signalling []. |
| Short Name | NTR_Sfrp3 |