Protein Domain : GREB1 IPR028422

Type  Family
Description  GREB1 (gene regulated in breast cancer 1 protein) is a ESR1 (estrogen receptor 1)-upregulated protein that may regulate estrogen action and it is associated with estrogen-stimulated cell proliferation [ ]. It acts as a regulator of hormone-dependent cancer growth in breast, ovarian and prostate cancers [, , , ]. This protein may be a target to inhibit tumour-promoting pathways both downstream and independent of ESR1 as a possible treatment strategy.This entry represents a protein family that includes Protein GREB1 and similar proteins from chordates.
Short Name  GREB1

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