Protein Domain : 5,10-methylenetetrahydrofolate reductase IPR004620

Type	Family
Description	This entry represents a family that includes bacterial 5,10-methylenetetrahydrofolate reductase (FADH).The enzyme activities methylenetetrahydrofolate reductase ( ) and 5,10-methylenetetrahydrofolate reductase (FADH) ( ) differ in that the former (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while the latter (assigned in many bacteria) is flexible with respect to the acceptor. Both generate 5-methyltetrahydrofolate from 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as one or the other, this family describes the subset of proteins found in prokaryotes, and currently designated 5,10-methylenetetrahydrofolate reductase (FADH) ( ). This protein is an FAD-containing flavoprotein [ ].
Short Name	MTHF_reductase_bac