Protein Domain : Thiazole biosynthesis domain IPR026340

Type  Domain
Description  The ThiI protein of Escherichia coli is a bifunctional protein in which most of the length of the protein is responsible for sulfurtransferase activity in 4-thiouridine modification to tRNA ( ). This rhodanese-like C-terminal domain, by itself, is able to synthesize the thiazole moiety during thiamin biosynthesis [ ]. Note that the invariant Cys residue in this domain is unusual in being required for both activities of the bifunctional ThiI protein.
Short Name  Thiazole_biosynth_dom

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