Protein Domain : Orai superfamily IPR038350

Type  Homologous_superfamily
Description  This entry includes Drosophila Orai and human Orai1, Orai2 and Orai3. ORAI-1 green fluorescent protein (GFP) reporters are co-expressed with STIM-1 (ER CA(2+) sensors) in the gonad and intestine. The protein has four predicted transmembrane domains with a highly conserved region between TM2 ad TM3. This conserved domain is thought to function in channel regulation. ORAI1-related proteins are required for the production of the calcium channel, CRAC, along with STIM1-related proteins [ ].
Short Name  Orai_sf

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

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