Protein Domain : AT-rich interactive domain-containing protein 4B, ARID/BRIGHT DNA binding domain IPR028853

Type  Domain
Description  AT-rich interactive domain-containing protein 4B (ARID4B) acts as a transcriptional repressor. It may function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes [ ]. It may play an integral part in the AR (androgen receptor) and RB (retinoblastoma) regulatory pathways involved in the regulation of Sertoli cell function and male fertility []. It is linked to tumor growth and metastasis [].This entry represents the AT-rich ARID/BRIGHT DNA binding domain of ARID4B.
Short Name  ARID4B_ARID/BRIGHT_DNA-bd
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