Protein Domain : TEL2, C-terminal domain superfamily IPR038528

Type	Homologous_superfamily
Description	This entry represents a conserved domain found in a group of proteins called telomere-length regulation TEL2, or clock abnormal protein-2, which are conserved from plants to humans. These proteins regulate telomere length and contribute to silencing of sub-telomeric regions [ ]. In vitro the protein binds to telomeric DNA repeats. Tel2 acts at an early step of the TEL1/ATM pathway of DNA damage signaling [ ]. The structure of Tel2 consists of HEAT-like helical repeats that assemble into two separate α-solenoids []. This entry represents the C-terminal solenoid which consists of eleven helices.
Short Name	TEL2_C_sf