Protein Domain : Choice-of-anchor A domain IPR026588

Type	Domain
Description	This domain may occur as essentially the full length of a protein, except for an N-terminal sequence and a C-terminal protein-sorting signal such as PEP-CTERM or LPXTG. Most often, the putative surface protein is longer, in which this domain is found N-terminal to repeating stalk domains in bacterial surface proteins. This is one of very few domains for which both anchoring domains occur, and designated choice-of-anchor A domain. The structure model of this domain is highly similar to the Ice_binding adhesive proteins ( ). However, some of the bacterial species in which this domain can be found, are less likely to be water-based and thus the function seems unlikely to be ice-binding. This domain is found in a Bacillus anthracis protein with the gene name BA_0871 or BASH2_04951, which was described to be collagen binding and to be involved in the bacterial pathogenicity []. BA0871, has five CNA-family protein B-type repeats toward the C terminus and an LPXTG cell wall attachment motif [].
Short Name	Choice_anch_A