v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This family includes G-protein coupled receptor 183 (GP183, also known as EBV-induced G-protein coupled receptor 2) and similar proteins such as the orphan receptor GP141 and G-protein coupled receptor homologue FPV206 from Fowlpox virus.GP183 is a receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols [ , , ]. It regulates migration of astrocytes and is involved in the communication between astrocytes and macrophages []. It may also act as a chemotactic receptor for some T-cells upon binding to 7-alpha,25-OHC ligand. Together with CXCR5, it mediates B-cell migration []. |
| Short Name | GP183-like |