Protein Domain : G-protein coupled receptor 183-like IPR047160

Type  Family
Description  This family includes G-protein coupled receptor 183 (GP183, also known as EBV-induced G-protein coupled receptor 2) and similar proteins such as the orphan receptor GP141 and G-protein coupled receptor homologue FPV206 from Fowlpox virus.GP183 is a receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols [ , , ]. It regulates migration of astrocytes and is involved in the communication between astrocytes and macrophages []. It may also act as a chemotactic receptor for some T-cells upon binding to 7-alpha,25-OHC ligand. Together with CXCR5, it mediates B-cell migration [].
Short Name  GP183-like

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0 Ontology Annotations

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