Protein Domain : Serine/arginine-rich splicing factor 11, RRM IPR034447

Type  Domain
Description  SRSF11, also known as SRp54 or p54, belongs to the SR proteins family. It is involved in bridge-complex formation and splicing by mediating protein-protein interactions across either introns or exons. SRSF11 has been identified as a tau exon 10 splicing repressor. It interacts with a purine-rich element in exon 10, and suppresses exon 10 inclusion by antagonizing Tra2beta, an SR-domain-containing protein that enhances exon 10 inclusion [ ]. SRSF11 has also been shown to associate with active telomerase through the interaction with TERC and directs it to nuclear speckles specifically during S phase []. This entry represents the RNA recognition motif (RRM) domain of SRSF11.
Short Name  RRM_SRSF11

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

1 Parent Features

0 Publications

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