v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS4 (Suppressor of cytokine signalling 4) is the substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins [ ]. SOCS4 and SOCS5 regulate epidermal growth factor receptor signaling [].This entry represents the SH3 domain of SOCS4. |
| Short Name | SOCS4_SH2 |