v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | The region is found towards the N terminus of a number of adaptor proteins that interact with Abl-family tyrosine kinases [ ]. More specifically, it is termed the homeo-domain homologous region (HHR), as it is similar to the DNA-binding region of homeo-domain proteins []. Other homeo-domain proteins have been implicated in specifying positional information during embryonic development, and in the regulation of the expression of cell-type specific genes []. The Abl-interactor proteins are thought to coordinate the cytoplasmic and nuclear functions of the Abl-family kinases, and seem to be involved in cytoskeletal reorganisation, but their precise role remains unclear []. |
| Short Name | Abl-interactor_HHR_dom |