v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | Testin contains a PET domain at the N terminus and three C-terminal LIM domains [ ]. It is a cytoskeleton associated focal adhesion protein that localizes along actin stress fibres, at cell-cell contact areas, and at focal adhesion plaques [, ]. Testin interacts with a variety of cytoskeletal proteins, including zyxin, mena, VASP, talin, and actin and is involved in cell motility and adhesion events. Knockout mice experiments have revealed a tumour repressor function. [, ].The entry represents the testin PET domain. It is a protein-protein interaction domain and PET containing proteins serve as adaptors or scaffolds to support the assembly of multimeric protein complexes. |
| Short Name | PET_testin |