Protein Domain : Chloride intracellular channel protein 2, C-terminal domain IPR030253

Type  Domain
Description  Chloride intracellular channel (CLIC) proteins are multifunctional and participate in a wide variety of signaling activities. CLIC proteins are able to convert from a water-soluble state to a membrane channel state [ ]. Chloride intracellular channel protein 2 (CLIC-2) is found in in most tissues except the brain, and is highly expressed in the lung, spleen, skeletal muscle and myocardium. It inhibits cardiac ryanodine receptor Ca2+ release channels [, , ]. It contains an intramolecular disulfide bond and exists as a monomer regardless of redox conditions [].This is the C-terminal helical domain.
Short Name  GST_C_CLIC-2

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3 Ontology Annotations

1 Parent Features

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