Protein Domain : Regulation of nuclear pre-mRNA domain-containing protein 1A/B IPR032337

Type  Domain
Description  Regulation of nuclear pre-mRNA domain-containing protein 1A/B (also known as CREPT , cell-cycle alteration and expression-elevated protein in tumour) belong to a family of eukaryotic transcriptional regulators that promote the binding of RNA-polymerase to the CYCLIN D1, CCDN1, promoter and other genes involved in the cell-cycle [ ]. It promotes the formation of a chromatin loop in the CYCLIN D1 gene, and is preferentially expressed in a range of different human tumours [].This entry represents the C-terminal coiled-coil domain which mediates the formation of homo and heterodimers [ ].
Short Name  RPR1A/B

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