Protein Domain : RING finger and transmembrane domain-containing protein 1/2 IPR044235

Type  Family
Description  This family represents RING finger and transmembrane domain-containing protein RNFT1 and RNTF2. RNFT1 is an E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, a mechanism that protects cells from ER stress-induced apoptosis. Misfolded proteins that have been accumulated in the ER are targeted for ubiquitination and selectively transported to the cytosol for degradation by a ubiquitin-proteasome system [ ]. The function of RNTF2 is not clear.
Short Name  RNFT1/2

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

0 Parent Features

0 Publications

USDA
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