Protein Domain : U3 snoRNP protein/Ribosome production factor 1 IPR044281

Type  Family
Description  This family represents the U3 small nucleolar ribonucleoprotein protein IMP4 and Ribosome production factor 1 RPF1 that belong to the IMP4 superfamily. This superfamily contains a Brix (biogenesis of ribosomes in Xenopus) domain, a region of 150-180 residues length, and it is characterised by the sigma70-like motif, a sequence motif first identified in the sigma70 family of prokaryotic transcription factors, which is sufficient to confer RNA binding activity [ , , ]. IMP4 is a component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) and it is required for the early cleavages during pre-18S ribosomal RNA processing [, ]. RPF1 is a essential protein involved in ribosome biogenesis [].
Short Name  IMP4/RPF1

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2 Ontology Annotations

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