Protein Domain : Uncharacterised protein family UPF0029, Impact, conserved site IPR020569

Type  Conserved_site
Description  This entry contains the protein Impact, which is a translational regulator that ensures constant high levels of translation under amino acid starvation. It acts by interacting with Gcn1/Gcn1L1, thereby preventing activation of Gcn2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. It is evolutionary conserved from eukaryotes to archaea [ ]. This signature pattern matches a conserved region.
Short Name  UPF0029_Impact_CS
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