Protein Domain : FMP27/BLTP2, N-terminal IPR019439

Type	Domain
Description	This entry includes FMP27 (also known as Hob1), C3H5.09c from S.pombe, Hobbit from fruit fly and BLTP2 from human (also known as KIAA0100), which are known as Hob proteins. They are tube-forming lipid transport proteins which bind to phosphatidylinositols and affects phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) distribution [ , , ]. They belong to the repeating β-groove (RBG) superfamily together with VPS13, ATG2, SHIP164, Csf1/BLTP1 proteins, which are all conserved lipid transfer proteins containing long hydrophobic grooves [, ]. They all share the same structure consisting of multiple repeating modules comprising five β-sheets followed by a loop.This entry represents the N-terminal of FMP27 and BLTP2.
Short Name	FMP27/BLTP2_N