Protein Domain : Interleukin-1 receptor-associated kinase 1-binding protein 1 IPR030312

Type  Family
Description  Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1BP1, also known as SIMPL) was originally identified in a yeast two-hybrid screen system [ ]. In mice, IRAK1BP1 inhibits inflammation by promoting nuclear translocation of NF-kappaB p50 []. In Haliotis diversicolor, IRAK1BP1 plays an important role in the adult abalone immune system and might be essential in embryo and larval development in abalone [].
Short Name  IRAK1BP1
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