Protein Domain : Type IV secretion system coupling protein TraD, DNA-binding domain IPR019476

Type  Domain
Description  The plasmid conjugative coupling protein TraD (also known as TrwB) is a basic integral inner-membrane nucleoside-triphosphate-binding protein. It is the structural prototype for the type IV secretion system coupling proteins, a family of proteins essential for macromolecular transport between cells [ ]. This protein forms hexamers from six structurally very similar protomers []. This hexamer contains a central channel running from the cytosolic pole (formed by the all-α domains) to the membrane pole ending at the transmembrane pore shaped by 12 transmembrane helices, rendering an overall mushroom-like structure. The TrwB all-α domain appears to be the DNA-binding domain of the structure.
Short Name  T4SS_TraD_DNA-bd

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