LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | The development of B and T cells depends on the rearrangement of variable (V), diversity (D), and joining (J) gene segments to produce mature Ig and T cellreceptor coding regions. This rearrangement process, known as V(D)J recombination is initiated by the complex, multi-domain proteins RAG1 andRAG2. The RAG proteins catalyze DNA cleavage in the first phase of the reaction using a recombination signal sequence (RSS) that flanks V, D and Jsegments [ , , ].RAG1 contains a zinc-binding dimerization domain immediately N-terminal to the catalytic core region, which in turn contains a putative DNA-binding domain at its N terminus. The dimerization domain consists of azinc C3HC4 RING finger and a C2H2 zinc RAG1-type finger.The C2H2 RAG1-type zinc finger contains the hallmarks of a classical zinc finger structure with a two stranded β-sheet and an α-helix []. |
| Short Name | RAG1_Znf |
