LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Conserved_site |
| Description | Bacterial membrane-bound nickel-dependent hydrogenases require a number of accessory proteins which are involved in their maturation [ ]. One of these proteins is generally known as HypA. HypA is a metallochaperone that binds nickel to bring it safely to its target. The nickel coordinates with four nitrogens within the protein. Four conserved cysteines towards the C terminus bind one zinc moiety, probably to stabilise the protein fold []. In Helicobacter pylori, HypA is involved in the maturation of both hydrogenase and urease []. Escherichia coli has two proteins that belong to this family, HypA and HybF []. A homologue, MJ0214, has also been found in a number of archaeal species, including the genome of Methanocaldococcus jannaschii (Methanococcus jannaschii).This entry represents a region from these proteins that contains two of the conserved cysteines. |
| Short Name | Hydgase_Ni_incorp_HypA/HybF_CS |
