Protein Domain : G2 and S phase-expressed protein 1, N-terminal IPR032768

Type  Domain
Description  This entry represents the N terminus of GTSE1 proteins. GTSE-1 (G2 and S phase-expressed-1) protein is specifically expressed during S and G2 phases of the cell cycle. It is mainly localised to the microtubules and when overexpressed delays the G2 to M transition. the full protein negatively regulates p53 transactivation function, protein levels, and p53-dependent apoptosis [, ]. This domain is found in eukaryotes, and is approximately 140 amino acids in length. There is a conserved FDFD sequence motif.
Short Name  GTSE1_N

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