Protein Domain : NKG2-D type II integral membrane protein IPR042169

Type  Family
Description  NKG2D is an activating receptor for triggering the NK cell cytotoxic activity [ ]. It binds to a variety of cell surface glycoproteins distantly related to MHC class I molecules, termed NKG2D ligands (NKG2DL). The expression of a certain ligand or a particular allelic variant is essential to drive a proper immune response []. The NKG2D/NKG2DL axis has been shown to be the potential therapeutic candidate for anticancer immunotherapy [, ].
Short Name  NKG2D
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