Protein Domain : Hydrogenase assembly chaperone, conserved site IPR019812

Type	Conserved_site
Description	The large subunit of [NiFe]-hydrogenase, as well as other nickel metalloenzymes, is synthesised as a precursor devoid of the metalloenzyme active site. This precursor then undergoes a complex post-translational maturation process that requires a number of accessory proteins. The hydrogenase expression/formation proteins (HupF/HypC) form a family of smallproteins that are hydrogenase precursor-specific chaperones required for this maturation process [ ]. They are believed to keep the hydrogenase precursor in a conformation accessible for metal incorporation [, ].The signature pattern for this entry is 9 residues in length, located at the N terminus; all the proteins matched by this pattern start with a conserved Met-Cys dipeptide.
Short Name	Hydgase_assmbl_chp_CS