v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | AlkB proteins are dioxygenases that repair alkylation damage to DNA and RNA [ ]. Nine mammalian AlkB homologues exist (ALKBH1-8, FTO), but only a subset functions as DNA/RNA repair enzymes [].This entry represents AlkB homologue 3 (ALKBH3, ABH3), which has a strong preference for single-stranded DNA also demethylates 1-methyladenine (1meA) and 3-methylcytosine (3meC) in RNA [ , , ]. ALKBH3 is overexpressed in various cancers and contributes to cancer cell survival [, , ]. |
| Short Name | ALKBH3 |