Protein Domain : Molecular chaperone regulator BAG-1 IPR017093

Type  Family
Description  This group represents a molecular chaperone regulator BAG-1 [ ]. BAG-1 contains a BAG domain that is formed by two antiparallel helices, while the third helix is extended away and stabilized by crystal-packing interactions []. BAG-family proteins contain a single BAG domain, except for human BAG-5 which has four BAG repeats. The BAG domain is a conserved region located at the C terminus of the BAG-family proteins that binds the ATPase domain of Hsc70/Hsp70. BAG family proteins regulate chaperone protein activities through their interaction with Hsc70/Hsp70 [ ].
Short Name  BAG-1

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