Protein Domain : Mga helix-turn-helix domain IPR007737

Type  Domain
Description  M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions [ ]. This domain is found in the centre of the Mga proteins. This domain is also found in a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins []. This is presumably a DNA-binding domain.
Short Name  Mga_HTH

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