Protein Domain : ELO family, conserved site IPR030457

Type	Conserved_site
Description	This entry represents a conserved site found in the ELO (Elongation of fatty acids protein) family members, such as:Mammalian proteins ELOVL1 (Elongation of very long chain fatty acids protein 1) to ELOVL4 [ ]. These proteins all seem to beinvolved in the synthesis of very long chain fatty acids. Yeast ELO1, ELO2 and ELO3 [ ]. They seem to be components of membrane-boundfatty acid elongation systems. Caenorhabditis elegans hypothetical protein C40H1.4.Caenorhabditis elegans hypothetical protein D2024.3.The proteins have from 271 to 435 amino acid residues. Structurally, they seem to be formed of three sections: a N-terminal region with two transmembranedomains, a central hydrophilic loop and a C-terminal region that contains from one to three transmembrane domains. This entry represents aconserved region that contains three histidines. This region is located in the hydrophilic loop.
Short Name	ELO_CS