LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This entry represents Lissencephaly-1 (LIS1) and homologues. LIS1 is required for nuclear migration in fungi, cell cycle progression in mammals, and the formation of a folded cerebral cortex in humans. They appear to regulate the mechanical behaviour of cytoplasmic dynein, the primary minus-end-directed microtubule motor [ ]. Proteins in this entry include:Platelet-activating factor acetylhydrolase IB subunit alpha, also known as Lissencephaly-1 protein [ ].Nuclear distribution protein PAC1 from budding yeasts [ ]. Fungal nuclear distribution protein nudF [ , ].Mutations in the LIS1 gene cause Lissencephaly-1, a classical lissencephaly characterised by agyria or pachygyria and disorganization of the clear neuronal lamination of normal six-layered cortex [ ]. |
| Short Name | Dynein_regulator_LIS1 |
