Protein Domain : Domain of unknown function DUF4472 IPR029329

Type	Domain
Description	This domain is found in proteins from Metazoa. Some proteins also carry kinesin-motor domains at their N terminus ( ). Proteins containing this domain include the coiled-coil domain-containing protein 78 (CCDC78), which is a component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles [ ]. CCDC78 does not have the kinesin-motor domain. Mutations in CCDC78 genes cause Myopathy, centronuclear, 4 (CNM4), which is a congenital muscle disorder characterised by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles [].
Short Name	DUF4472