Protein Domain : Mitochondrial intermembrane space import and assembly protein 40 IPR039289

Type  Family
Description  Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) is a chaperone and catalyses the formation of disulfide bonds in proteins within the mitochondrial intermembrane space (IMS) such as COX17 [ ], COX19 [], MICU1 [] and GFER []. A precursor of one of these proteins in a reduced state is imported into the mitochondrion where it associates with CHCHD4 forming a transient intermolecular disulfide bridge. This leads to oxidation of the precursor, formation of an intramolecular disulfide bond and the folding in the IMS [].This entry also includes the uncharacterized protein F42H10.2 from Caenorhabditis elegans.
Short Name  CHCHD4

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

0 Parent Features

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