Protein Domain : Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter IPR005948

Type  Family
Description  Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. Most of the bacterial ABC (ATP-binding cassette) importers are composed of one or two transmembrane permease proteins, one or two nucleotide-binding proteins and a highly specific periplasmic solute-binding protein. In Gram-negative bacteria the solute-binding proteins are dissolved in the periplasm, while in archaea and Gram-positive bacteria, their solute-binding proteins are membrane-anchored lipoproteins [ , ].This entry includes thiB from Proteobacteria and its homologues from Archaea, Actinobacteria, Euryarchaeota and other bacteria. ThiB is a thiamine/thiamine pyrophosphate-binding protein and part of the ABC transporter complex ThiBPQ involved in thiamine import. ThiBPQ is required for transport of thiamine and thiamine pyrophosphate in Salmonella typhimurium []. This entry also includes tbpA from E. coli [].
Short Name  ThiB-like

1 Child Features

0 Gene Families

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2 Ontology Annotations

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