v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | The tripartite motif-containing protein (Trim) family is defined by the presence of a common domain structure composed of a RING finger, a B-box, and a coiled-coil motif [ ]. Trim36 is a E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. It interacts with centromere protein-H, one of the kinetochore proteins and is involved in chromosome segregation and cell cycle regulation. This protein has been associated with anencephaly [, , ]. It may play a role in the acrosome reaction and fertilisation [, ].This entry represents the HC-RING finger found at the N-terminal of Trim36. |
| Short Name | Trim36_HC-RING |