Protein Domain : SXP/RAL-2 family protein Ani s 5-like, cation-binding domain IPR003677

Type  Domain
Description  This domain is found in proteins from nematodes, including SXP/RAL-2 family protein Ani s 5 (ANIS5) from Anisakis simplex, and comprises two conserved motifs: SXP1 and SXP2 [ ]. Although the function of this domain is not clear, structural information from ANIS5 revealed an alpha helical arrangement with a Calmodulin-like fold. Functional studies indicates that ANIS5 can bind magnesium and calcium, suggesting that this domain plays a role in cation binding []. These proteins are interesting targets to develop control strategies against the diseases caused by parasites.
Short Name  ANIS5_cation-bd
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