LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | The B-cell antigen receptor (BCR) consists of the membrane-bound immunoglobulin (mIg) comprising two heavy (H) and two light (L) chains and the signal-transducing Igalpha/Igbeta (CD79a/CD79b) heterodimer. This entry includes CD79a and CD79b. They contain an immunoreceptor tyrosine-based activation motif (ITAM) with two conserved tyrosines that are crucial for the development and maintenance of mature B cells [ ]. Homologues are known from vertebrates.This family also includes Transmembrane and immunoglobulin domain-containing protein 2 (TMIGD2) which plays a role in cell-cell interaction, cell migration, and angiogenesis. It seems structurally related to CD79a/b based on structure prediction. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. It enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade [ , ]. |
| Short Name | CD79a/CD79b |
