LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | Doublecortin domain-containing protein 2 (DCDC2) interacts with the mediator of Wnt signalling dishevelled. The overexpression of DCDC2 inhibits beta-catenin-dependent Wnt signalling []. It also plays an important role in hair cell kinocilia and supporting cell primary cilia length regulation, likely via its role in microtubule formation and stabilisation []. It also affects length and signalling of primary cilia in neurons and has been associated with learning disabilities [, ]. Genetic variation in humans is associated with neonatal sclerosing cholangitis, a rare biliary disease leading to liver transplantation in childhood [].This entry represents the doublecortin-like domain 2 of DCDC2. |
| Short Name | DCDC2_DCX_dom2 |
