Protein Domain : NIDO domain IPR003886

Type  Domain
Description  The ~180-residue NIDO domain is an extracellular domain of unknown function, found in nidogen (entactin) and hypothetical proteins. The NIDO domain isfound in association with other domains, such as nidogen G2 β-barrel ( ), thyroglobulin type-1 ( ), LDLRB ( ), AMOP ( ), EGF-like ( ), VWFD, IPT/TIG, or sushi/CCP/SCR () [ , , , ].Some proteins known to contain a NIDO domain are listed below: Vertebrate nidogen-1 (NID-1) or entactin, a sulphated glycoprotein widely distributed in basement membranes.Vertebrate nidogen-2 (NID-2) or osteonidogen, a cell adhesion glycoprotein which is widely distributed in basement membranes.Vertebrate alpha-tectorin.Mammalian mucin-4 (MUC4), a highly glycosylated membrane-bound protein.Xenopus ID14, a putative matrix protein.
Short Name  NIDO_dom

0 Child Features

0 Gene Families

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1 Ontology Annotations

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