Protein Domain : WWE domain superfamily IPR037197

Type  Homologous_superfamily
Description  The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein-protein interactions in ubiquitin and ADP ribose conjugation systems. This domain is found as a tandem repeat at the N-terminal of Deltex, a cytosolic effector of Notch signalling thought to bind the N-terminal of the Notch receptor [ ]. It is also found as an interaction module in protein ubiquination and ADP ribosylation proteins [].Structurally, the WWE domain has a beta(2)-α-β(4) fold with antiparallel folded β-sheet (half-barrel).
Short Name  WWE_dom_sf

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

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