Protein Domain : Caskin-1, SH3 domain IPR035495

Type  Domain
Description  This entry represents the SH3 domain of Caskin-1 (CASK-interacting protein 1).Caskin-1 and Caskin-2 are multidomain proteins containing six N-terminal ankyrin repeats, a single SH3 domain, and two sterile alpha motif (SAM) domains followed by a long proline-rich sequence and a short conserved C-terminal domain. Caskin-1 may link the scaffolding protein CASK to downstream intracellular effectors [ ]. Caskin-1 polymerises, via the tandem SAM domains, to form long, 8 nM wide fibres, upon which other proteins can assemble [].
Short Name  Caskin1_SH3

0 Child Features

0 Gene Families

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0 Ontology Annotations

1 Parent Features

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