Protein Domain : BAG family molecular chaperone regulator 2 IPR037689

Type  Family
Description  This entry represents the BAG2 protein, which belongs to the BAG family. BAG2 acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release [ , ].BAG-family proteins contain a single BAG domain, except for human BAG-5 which has four BAG repeats. The BAG domain is a conserved region located at the C terminus of the BAG-family proteins that binds the ATPase domain of Hsc70/Hsp70. BAG family proteins regulate chaperone protein activities through their interaction with Hsc70/Hsp70 [ ].
Short Name  BAG2

0 Child Features

0 Gene Families

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2 Ontology Annotations

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