Protein Domain : Heme-binding protein Shr-like, Hb-interacting domain IPR011432

Type  Domain
Description  This entry represents the Hb-interacting domain (HID), which is found duplicated in Heme-binding protein Shr from Streptococcus pyogenes, a potentially lethal human pathogen, and in one to six copies in other uncharacterised bacterial proteins. Shr is a virulence factor that captures Hb and binds to the oxidized form of heme through an N-terminal region that contains two copies of this domain. HID shows a β-sandwich-type fold in which two antiparallel β-sheets are flanked by an α-helix [ ].
Short Name  Shr-like_HID

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0 Gene Families

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USDA
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